Debré B, Steg A
Nouv Presse Med. 1979 Oct 29;8(41):3341-3.
It has now been clearly demonstrated that cryptorchidism is accompanied by a very marked increase in malignancy of the ectopic testis as well as in that in place. Amongst 80 patients undergoing surgery for carcinoma of the testis 14 (17.5%) had a past history of unilateral undescended. The risk of malignancy developing in an ectopic testis is 12 to 48 times greater than that of a testis which has descended normally. It would appear that the higher the position of the testis, the greater is the risk. Orchidopexy may decreased the risk if performed before the age of 11. When the tumour is situated in an ectopic testis, the clinical picture is often misleading. When the ectopic testis has been brought down the special feature of these tumours is the frequency of spread to inguinal lymph nodes. In terms of its basic principles the treatment of these tumours does not differ from that of those affecting normal testis. The aetiology of these tumours remains uncertain. There would seem to be a consensus in favour of a disgenetic origin, possible secondary to hormonal deficiency.
现已明确证实，隐睾症会伴随着异位睾丸以及正常位置睾丸的恶性肿瘤发生率显著增加。在80例接受睾丸癌手术的患者中，有14例（17.5%）有单侧隐睾病史。异位睾丸发生恶性肿瘤的风险比正常下降的睾丸高12至48倍。睾丸位置越高，风险似乎就越大。如果在11岁之前进行睾丸固定术，可能会降低风险。当肿瘤位于异位睾丸时，临床表现往往具有误导性。当异位睾丸被降入阴囊后，这些肿瘤的一个特殊特征是向腹股沟淋巴结转移的频率较高。就其基本原则而言，这些肿瘤的治疗与影响正常睾丸的肿瘤并无不同。这些肿瘤的病因仍不确定。似乎有一种共识支持发育异常起源，可能继发于激素缺乏。
