Kukulansky T, Yagil G
Horm Metab Res. 1979 Jan;11(1):14-9. doi: 10.1055/s-0028-1092673.
Regulation of glucose-6-phosphate dehydrogenase and fatty acid synthetase activity in mouse liver is examined in diabetic and normal mice. Up to a 4-fold increase of both enzymes can be observed in streptozotocin diabetic mice when transferred to a fatless, inducing diet. Administration of insulin does not increase enzyme activity at several doses and under a variety of conditions. This is a strong indication that insulin is not a necessary component of the induction system.
在糖尿病小鼠和正常小鼠中研究了葡萄糖-6-磷酸脱氢酶和脂肪酸合成酶活性的调节。当链脲佐菌素诱导的糖尿病小鼠改用无脂肪诱导饮食时，可观察到这两种酶的活性都增加了4倍。在几种剂量和各种条件下给予胰岛素均未增加酶活性。这有力地表明胰岛素不是诱导系统的必要组成部分。
