百日咳博德特氏菌诱导的白细胞增多和淋巴细胞增多的研究。I. 百日咳诱导的白细胞增多小鼠循环细胞的放射自显影分析。
Studies on the leukocytosis and lymphocytosis induced by Bordetella pertussis. I. Radioautographic analysis of the circulating cells in mice undergoing pertussis-induced hyperleukocytosis.
作者信息
Morse S I, Riester S K
出版信息
J Exp Med. 1967 Mar 1;125(3):401-8. doi: 10.1084/jem.125.3.401.
Abstract
By the use of radioautographic techniques it was shown that the lymphocytosis induced by Bordetella pertussis in mice was not caused by an increased production of lymphocytes but was primarily due to the entry into the circulation of mature cells from tissue pools. The accompanying polymorphonuclear leukocytosis was due to both proliferation of myeloid elements and entry of mature cells from tissue reserves, with the former the predominant mechanism.
摘要
通过放射自显影技术表明，百日咳博德特氏菌在小鼠中诱导的淋巴细胞增多不是由淋巴细胞产生增加引起的，而是主要由于成熟细胞从组织库进入循环所致。伴随的多形核白细胞增多是由于髓系成分的增殖和成熟细胞从组织储备进入，前者是主要机制。
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