百日咳博德特氏菌引起的白细胞增多和淋巴细胞增多的研究。II. 百日咳疫苗对小鼠胸导管淋巴液和淋巴细胞的影响。
Studies on the leukocytosis and lymphocytosis induced by Bordetella pertussis. II. The effect of pertussis vaccine on the thoracic duct lymph and lymphocytes of mice.
作者信息
Morse S I, Riester S K
出版信息
J Exp Med. 1967 Apr 1;125(4):619-28. doi: 10.1084/jem.125.4.619.
Abstract
The 24 hr volume flow, cell concentration, and total cell output of thoracic duct fluid from mice with pertussis-induced hyperlymphocytosis were markedly reduced when compared with values obtained in normal animals. An increase in the number of circulating lymphocytes occurred in several of the pertussis-treated mice despite the presence of an indwelling thoracic duct cannula. The drainage from such animals also showed a reduced cell concentration and total cell output. It is suggested that lymphocyte recirculation may be minimal in pertussis-induced lymphocytosis, and the evidence obtained also suggests that lymphocytes may enter the blood stream by direct routes during the course of the reaction.
摘要
与正常动物相比，百日咳诱导的高淋巴细胞血症小鼠胸导管液的24小时体积流量、细胞浓度和总细胞输出量显著降低。尽管有胸导管插管，但几只接受百日咳治疗的小鼠循环淋巴细胞数量仍增加。这些动物的引流液也显示细胞浓度和总细胞输出量降低。提示在百日咳诱导的淋巴细胞增多症中淋巴细胞再循环可能极少，所获得的证据还提示在反应过程中淋巴细胞可能通过直接途径进入血流。
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Studies on the leukocytosis and lymphocytosis induced by Bordetella pertussis. I. Radioautographic analysis of the circulating cells in mice undergoing pertussis-induced hyperleukocytosis.百日咳博德特氏菌诱导的白细胞增多和淋巴细胞增多的研究。I. 百日咳诱导的白细胞增多小鼠循环细胞的放射自显影分析。
J Exp Med. 1967 Mar 1;125(3):401-8. doi: 10.1084/jem.125.3.401.
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