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[代谢性酸中毒和碱中毒时的血糖与缺氧动态变化(实验数据)]

[Blood sugar and hypoxic dynamics in metabolic acidosis and alkalosis (experimental data)].

作者信息

Iluchev D

出版信息

Eksp Med Morfol. 1975;14(2):98-106.

PMID:4290
Abstract

The dynamics of the glucose concentration and arterovenous glucose gradient was examined during different metabolic deviations in the acid-base balance. The metabolitic acidosis increased the level of sugar in the blood. A definite influence on the latter had the gravity of the acidosis and to a certain degree its pathogenetic form. The arterio-venous glucose difference changed from negative to positive with the increase of proton activity. The type of the peripheral hypoxic structure, formed during the state of acidosis influenced both the glucose gradient and its quantitative relations to the acid-base and oxygen indices. The sugar content in the blood during metabolitic alcalosis was not changed significantly. There was an increase in the arterio-venous gradient and inverse correlation between the glucose level and the arterio-venous oxygen difference with the increase of the bicarbonate concentration.

摘要

在酸碱平衡的不同代谢偏差期间,对葡萄糖浓度和动静脉葡萄糖梯度的动态变化进行了研究。代谢性酸中毒会使血糖水平升高。酸中毒的严重程度及其某种程度上的发病形式对血糖水平有一定影响。随着质子活性的增加,动静脉葡萄糖差值从负值变为正值。酸中毒状态下形成的外周缺氧结构类型,既影响葡萄糖梯度,也影响其与酸碱和氧指标的定量关系。代谢性碱中毒期间,血液中的糖含量无显著变化。随着碳酸氢盐浓度的增加,动静脉梯度增加,且葡萄糖水平与动静脉氧差值呈负相关。

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