McLean D M, Bannatyne R M, Givan K F
Can Med Assoc J. 1967 Jun 3;96(22):1449-53.
Myxoviruses including 150 strains of parainfluenza 1, 15 of parainfluenza 3 and five of influenza B virus were isolated from nasopharyngeal secretions obtained from 300 children less than 3 years of age who developed acute laryngotracheobronchitis during the preceding 48 hours. The patients were examined between October 1966 and January 1967, the peak monthly rate of virus isolation (67%) occurring during January. Parainfluenza 1 virus was isolated from air obtained in the vicinity of one of 30 children whose nasopharyngeal secretions yielded this agent. Samples comprising 150 litres of air were collected for virus assay by placing an Andersen sampler about 60 cm. from the child's face inside an oxygen tent which surrounded the patient. These findings confirm previous observations that parainfluenza 1 virus is the dominant agent associated with acute laryngotracheobronchitis in children in Toronto, and they show that this virus is disseminated in the air.
从300名3岁以下儿童的鼻咽分泌物中分离出黏液病毒，其中包括150株副流感病毒1型、15株副流感病毒3型和5株乙型流感病毒。这些儿童在之前48小时内患了急性喉气管支气管炎。对这些患者的检查时间为1966年10月至1967年1月，病毒分离的月峰值率（67%）出现在1月。在30名鼻咽分泌物中检出该病原体的儿童中，有1名儿童附近空气中分离出了副流感病毒1型。通过将安德森采样器放置在包围患者的氧气帐篷内距儿童面部约60厘米处，收集了150升空气样本用于病毒检测。这些发现证实了之前的观察结果，即副流感病毒1型是多伦多儿童急性喉气管支气管炎的主要病原体，并且表明这种病毒可在空气中传播。
