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Metabolic degradation of 3,4-benzopyrene in the cultures of normal and neoplastic fibroblasts.

作者信息

Andrianov L N, Belitsky G A, Ivanova O J, Khesina A Y, Khitrovo S S, Shabad L M, Vasiliev J M

出版信息

Br J Cancer. 1967 Sep;21(3):566-75. doi: 10.1038/bjc.1967.66.

DOI:10.1038/bjc.1967.66
PMID:4293324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2008029/
Abstract
摘要

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The carcinogen benzo(e)pyrene is metabolized by DM15 cells without an uncoupling effect on their gap junctions.致癌物苯并（e）芘可被DM15细胞代谢，且对其间隙连接无解偶联作用。
Cell Biol Toxicol. 1993 Apr-Jun;9(2):131-40. doi: 10.1007/BF00757575.
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Aryl hydrocarbon hydroxylase and polycyclic hydrocarbon tumorigenesis: effect of the enzyme inhibitor 7,8-benzoflavone on tumorigenesis and macromolecule binding.芳基烃羟化酶与多环烃肿瘤发生：酶抑制剂7,8-苯并黄酮对肿瘤发生及大分子结合的影响
Proc Natl Acad Sci U S A. 1972 Apr;69(4):824-8. doi: 10.1073/pnas.69.4.824.
3
Enzymatic hydroxylation of benzopyrene and its relationship to cytotoxicity.苯并芘的酶促羟基化作用及其与细胞毒性的关系。
Proc Natl Acad Sci U S A. 1969 Dec;64(4):1188-94. doi: 10.1073/pnas.64.4.1188.
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The effect of complete carcinogens on intercellular transfer of lucifer yellow in fibroblast culture.完全致癌物对成纤维细胞培养中荧光素黄细胞间转移的影响。
Cell Biol Toxicol. 1990 Jan;6(1):47-61. doi: 10.1007/BF00135026.
5
Influence of diet on breast cancer size and morphology in rats treated with DMBA.饮食对经二甲基苯蒽（DMBA）处理的大鼠乳腺癌大小和形态的影响。
Arch Gynecol Obstet. 1991;249(2):51-8. doi: 10.1007/BF02390362.

本文引用的文献

1
Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence.仓鼠细胞克隆的多瘤病毒转化——对影响细胞感受态的遗传因素的研究
Virology. 1962 Feb;16:147-51. doi: 10.1016/0042-6822(62)90290-8.
2
METABOLISM OF DRUGS IN RELATION OF CARCINOGENICITY.与致癌性相关的药物代谢
Ann N Y Acad Sci. 1965 Mar 12;123:125-40. doi: 10.1111/j.1749-6632.1965.tb12250.x.
3
METABOLISM OF DRUGS AND TOXIC SUBSTANCES.药物与有毒物质的代谢
Annu Rev Biochem. 1964;33:571-96. doi: 10.1146/annurev.bi.33.070164.003035.
4
THE COMPARATIVE CARCINOGENICITIES OF 2-ACETYLAMINOFLUORENE AND ITS N-HYDROXY METABOLITE IN MICE, HAMSTERS, AND GUINEA PIGS.2-乙酰氨基芴及其N-羟基代谢物在小鼠、仓鼠和豚鼠中的致癌性比较
Cancer Res. 1964 Dec;24:2018-31.
5
[EFFECT OF 7,12-DIMETHYLBENZO(ALPHA)ANTHRACENE ON CULTURE OF NORMAL AND CANCER TISSUES].[7,12-二甲基苯并(α)蒽对正常组织和癌组织培养的影响]
Vopr Onkol. 1964;10:55-60.
6
PHOTODYNAMIC TOXICITY OF POLYCYCLIC AROMATIC HYDROCARBONS IN TISSUE CULTURE.多环芳烃在组织培养中的光动力毒性
Cancer Res. 1964 Aug;24:1249-59.
7
DIFFERENTIAL TOXICITY RESPONSE OF NORMAL AND NEOPLASTIC CELLS IN VITRO TO 3,4-BENZOPYRENE AND 3-METHYLCHOLANTHRENE.正常细胞与肿瘤细胞在体外对3,4-苯并芘和3-甲基胆蒽的毒性反应差异
Br J Cancer. 1964 Mar;18(1):159-64. doi: 10.1038/bjc.1964.18.
8
IN VITRO CELL TRANSFORMATION WITH CHEMICAL CARCINOGENS.化学致癌物诱导的体外细胞转化
Nature. 1963 Dec 21;200:1182-4. doi: 10.1038/2001182a0.
9
SENSITIVITY OF NORMAL AND NEOPLASTIC CELLS TO THE DAMAGING ACTION OF CARCINOGENIC SUBSTANCES: A REVIEW.正常细胞与肿瘤细胞对致癌物质损伤作用的敏感性：综述
J Natl Cancer Inst. 1963 Nov;31:1123-51.
10
Substrate-induced synthesis and other properties of benzpyrene hydroxylase in rat liver.大鼠肝脏中苯并芘羟化酶的底物诱导合成及其他特性
J Biol Chem. 1957 Oct;228(2):753-66.