Sung C S, Hu C B
J Biomed Mater Res. 1979 Jan;13(1):45-55. doi: 10.1002/jbm.820130107.
The effect of the exposure to air or to the substrate during the solvent casting process on the surface chemical composition of Avcothane, a blood compatible biomaterial, was studied by employing Auger electron spectroscopy. The surface layer of 10-15A thickness was analyzed without sputtering, but for the studies probing a deeper layer, argon ion sputtering at a low enough voltage to prevent artifacts was utilized. It is found that the air facing surface which is the blood contact surface contains a greater amount of silicone polymer and a much lower amount of the urethane hard segment in the first 10-15A-deep layer than in the comparably thick layer of the substrate surface. However, the depth-composition profile obtained by sputtering indicate that, probably at a deeper depth, the chemical compositions in terms of silicone polymer and hard segment is comparable both in the air side and the substrate side.
通过俄歇电子能谱研究了溶剂浇铸过程中暴露于空气或基材对血液相容性生物材料Avcothane表面化学成分的影响。未进行溅射分析了厚度为10 - 15埃的表面层，但对于探测更深层的研究，使用了足够低电压的氩离子溅射以防止产生假象。研究发现，作为血液接触表面的面向空气的表面，在最初10 - 15埃厚的表层中，硅氧烷聚合物的含量比基材表面相同厚度层中的含量更高，而聚氨酯硬段的含量则低得多。然而，通过溅射获得的深度组成分布表明，可能在更深的深度，空气侧和基材侧的硅氧烷聚合物和硬段的化学成分是相当的。
