Corner A H, Greig A S, Hill D P
Can J Comp Med Vet Sci. 1967 Dec;31(12):320-30.
Mastitis was produced in three first calf heifers by inoculation of the udder with the virus of infectious bovine rhinotracheitis. These animals were killed at different times during the course of the disease and tissues were harvested and examined histologically. The basic lesion resulted from the necrotizing effect of the virus upon the epithelial cells of the alveoli and ducts. Eosinophilic intranuclear inclusion bodies were demonstrated in tissues from animals killed at three and six days postinoculation, but not at nine days. Of interest was the presence of a large Reed-Sternberglike cell in tissues of the last two animals killed.
通过向三头初产小母牛的乳房接种传染性牛鼻气管炎病毒来诱发乳腺炎。在疾病过程中的不同时间处死这些动物，采集组织并进行组织学检查。基本病变是由病毒对肺泡和导管上皮细胞的坏死作用引起的。在接种后三天和六天处死的动物组织中发现了嗜酸性核内包涵体，但在九天时未发现。有趣的是，在最后处死的两只动物的组织中存在一个大的里德-施特恩贝格样细胞。
