De Jong R H, Robles R, Morikawa K I
Science. 1968 May 17;160(3829):768-9. doi: 10.1126/science.160.3829.768.
A paralyzing dose of gallamine (Flaxedil) (1 to 2 milligrams per kilogram of body weight) has no effect on synaptic transmission in the cat's spinal cord. In spinal cats ventilated with oxygen, we stimulated a dorsal spinal root and recorded the compound ventral root potential. The reflex potential was not affected by 6.25 milligrams of gallamine per kilogram. Giving 12.5 milligrams of gallamine per kilogram had no significant effect on the monosynaptic spike height, but the polysynaptic response rose briefly to 12 percent above control. Increased magnitude of the polysynaptic response appeared related to a concomitant rise in blood pressure.
麻痹剂量的加拉明（三碘季铵酚）（每千克体重1至2毫克）对猫脊髓中的突触传递没有影响。在用氧气通气的脊髓猫中，我们刺激背侧脊髓神经根并记录复合腹侧神经根电位。每千克6.25毫克的加拉明对反射电位没有影响。每千克给予12.5毫克的加拉明对单突触棘波高度没有显著影响，但多突触反应短暂上升至比对照高12%。多突触反应幅度的增加似乎与血压的同时升高有关。
