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人侵袭性移行细胞癌中肿瘤基质界面附近的紧密连接。

Tight junctions adjacent to tumor stromal interface in human invasive transitional cell carcinomas.

作者信息

Alroy J

出版信息

Virchows Arch B Cell Pathol Incl Mol Pathol. 1979 Jun 29;30(3):289-96. doi: 10.1007/BF02889109.

DOI:10.1007/BF02889109
PMID:43009
Abstract

Tight junctions adjacent to the tumor stromal interface in invading neoplastic cells of human urinary bladder carcinomas were observed. Basal lamina, collagen and elastic fibers, and cellular debris were found next to the tight junctions. An association between microenvironment (i.e., tumor necrosis) of the invading neoplastic cells and tight junction locations was suggested.

摘要

在人类膀胱癌侵袭性肿瘤细胞中观察到紧邻肿瘤基质界面的紧密连接。在紧密连接旁发现了基膜、胶原纤维和弹性纤维以及细胞碎片。提示侵袭性肿瘤细胞的微环境（即肿瘤坏死）与紧密连接位置之间存在关联。

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