Caunt A E
Br J Exp Pathol. 1969 Feb;50(1):26-31.
V-Z virus has been propagated in embryonic human skin, lung and kidney grafted on the chorio-allantois of hens' eggs or maintained as organ cultures The histological changes produced resemble those in the intact human host and the virus produced is cell-free as it is in vesicle fluid. It is suggested that organ cultures may provide a useful model for investigating virus synthesis but the method has not been found practical for the large scale production of cell-free virus in the laboratory.
水痘-带状疱疹病毒已在移植于鸡胚绒毛尿囊膜上的人胚胎皮肤、肺和肾中增殖，或作为器官培养物维持。所产生的组织学变化类似于完整人类宿主中的变化，所产生的病毒与水疱液中的病毒一样无细胞。有人认为，器官培养可能为研究病毒合成提供一个有用的模型，但尚未发现该方法在实验室大规模生产无细胞病毒方面切实可行。
