Dewson J H, Dement W C, Wagener T E, Nobel K
Science. 1967 Apr 21;156(3773):403-6. doi: 10.1126/science.156.3773.403.
Three adult cats were deprived of rapid eye movement sleep for six separate periods of up to 32 days. Animals were allowed normal amouints of sleeping time during which rapid eye movement sleep was interrupted, whenever it occurred, by human observers who continually monitored the animals and their electrocortical activity. Cortical responses evoked by pairs of acoustic clicks were recorded during wakefulness. Recovery functions derived from these data were facilitated during periods of deprivation of rapid eye movement sleep and returned to base-line values when animals were allowed normal amounts of this sleep phase. This change was noted repeatedly within, as well as between, subjects. It did not occur during control periods when non-rapid eye movement sleep was interrupted on identical schedules, nor did it occur when the cats were deprived of all sleep for 22 hours a day for 5 days.
三只成年猫在六个不同时期被剥夺快速眼动睡眠，每次剥夺时间长达32天。在动物正常睡眠时间内，每当快速眼动睡眠出现时，就会被人类观察者打断，这些观察者持续监测动物及其脑电活动。在清醒状态下记录由成对的听觉滴答声诱发的皮层反应。从这些数据得出的恢复功能在快速眼动睡眠剥夺期间得到促进，当动物被允许进入正常量的该睡眠阶段时，恢复功能又回到基线值。这种变化在受试者内部以及受试者之间都反复出现。当按照相同时间表打断非快速眼动睡眠时，在对照期内并未出现这种变化，当猫每天被剥夺所有睡眠22小时，持续5天时，也未出现这种变化。
