通过在BHK21细胞的组织培养中进行修饰和克隆来开发一种减毒口蹄疫病毒疫苗。 - Suppr

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The development of an attenuated foot-and-mouth disease virus vaccine by modification and cloning in tissue cultures of BHK21 cells.

作者信息

Mowat G N, Barr D A, Bennett J H

出版信息

Arch Gesamte Virusforsch. 1969;26(4):341-54. doi: 10.1007/BF01250944.

DOI:10.1007/BF01250944

PMID:4306372

Abstract

摘要

相似文献

The development of an attenuated foot-and-mouth disease virus vaccine by modification and cloning in tissue cultures of BHK21 cells.通过在BHK21细胞的组织培养中进行修饰和克隆来开发一种减毒口蹄疫病毒疫苗。

Arch Gesamte Virusforsch. 1969;26(4):341-54. doi: 10.1007/BF01250944.

Enhancement by diethylamineothyl-dextran of the plaque-forming activity of foot-and-mouth disease virus-antibody complexes in pig kidney IB-RS-2 cells.二乙胺乙基葡聚糖对猪肾IB-RS-2细胞中口蹄疫病毒-抗体复合物蚀斑形成活性的增强作用。

Arch Virol. 1977;55(4):251-61. doi: 10.1007/BF01315047.

[Demonstration of antibody-synthesizing cells in mice and swine by means of local hemolysis in gel following immunization with foot-and-mouth disease virus and vaccine].[通过口蹄疫病毒和疫苗免疫后凝胶内局部溶血法在小鼠和猪中展示抗体合成细胞]

Zentralbl Bakteriol Orig A. 1974;227(1-4):420-5.

Development of a methodology for the production of foot- and- mouth disease virus from BHK21 C13 monolayer cells grown in a 100 l (20 m2) glass sphere propagator.一种从在100升（20平方米）玻璃球体增殖器中培养的BHK21 C13单层细胞生产口蹄疫病毒方法的开发。

Dev Biol Stand. 1979;42:113-9.

The role of small ruminants in the epidemiology and transmission of foot-and-mouth disease.小型反刍动物在口蹄疫流行病学及传播中的作用。

Vet J. 1999 Jul;158(1):6-13. doi: 10.1053/tvjl.1998.0338.

Response of sheep vaccinated with large doses of vaccine to challenge by airborne foot and mouth disease virus.大剂量接种疫苗的绵羊对空气传播的口蹄疫病毒攻击的反应。

Vaccine. 1984 Jun;2(2):157-61. doi: 10.1016/0264-410x(84)90008-2.

Interferon inducers and foot-and-mouth disease vaccines: influence of two synthetic polynucleotides on antibody response and immunity in guinea pigs and swine.干扰素诱导剂与口蹄疫疫苗：两种合成多核苷酸对豚鼠和猪抗体反应及免疫力的影响

Can J Comp Med. 1977 Jan;41(1):117-21.

Experimental foot-and-mouth disease in sheep and goats: an epizootiological model.绵羊和山羊的实验性口蹄疫：一种动物流行病学模型。

Arch Gesamte Virusforsch. 1972;38(1):85-96. doi: 10.1007/BF01241358.

Construction and evaluation of an attenuated vaccine for foot-and-mouth disease: difficulty adapting the leader proteinase-deleted strategy to the serotype O1 virus.口蹄疫减毒活疫苗的构建与评价：将缺失前导蛋白酶策略应用于O1型病毒存在困难

Virus Res. 1998 May;55(1):49-60. doi: 10.1016/s0168-1702(98)00031-8.

[Immunobiological properties of strains of foot-and-mouth disease virus multiplying in cell cultures].[在细胞培养物中增殖的口蹄疫病毒毒株的免疫生物学特性]

Veterinariia. 1975 May(5):53-5.

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B and T Cell Epitopes of the Incursionary Foot-and-Mouth Disease Virus Serotype SAT2 for Vaccine Development.入侵性口蹄疫病毒血清型 SAT2 的 B 和 T 细胞表位，用于疫苗开发。

Viruses. 2023 Mar 21;15(3):797. doi: 10.3390/v15030797.

Requirements for improved vaccines against foot-and-mouth disease epidemics.针对口蹄疫疫情的改良疫苗的要求。

Clin Exp Vaccine Res. 2013 Jan;2(1):8-18. doi: 10.7774/cevr.2013.2.1.8. Epub 2013 Jan 15.

A safe foot-and-mouth disease vaccine platform with two negative markers for differentiating infected from vaccinated animals.一种安全的口蹄疫疫苗平台，具有两个阴性标记物，用于区分感染动物和接种疫苗动物。

J Virol. 2012 Nov;86(21):11675-85. doi: 10.1128/JVI.01254-12. Epub 2012 Aug 22.

The use of interferon production as a marker in the development of a modified strain of foot-and-mouth disease virus.将干扰素产生用作口蹄疫病毒改良株研发中的一个标志物。

Arch Gesamte Virusforsch. 1968;23(1):12-9. doi: 10.1007/BF01242109.

Homologous interference by a foot-and-mouth disease virus strain attenuated for cattle.口蹄疫病毒株对牛的同源干扰（该病毒株对牛已减毒）

Arch Virol. 1985;86(3-4):291-301. doi: 10.1007/BF01309833.

本文引用的文献

Growth of foot-and-mouth disease virus in a fibroblastic cell line derived from hamster kidneys.口蹄疫病毒在源自仓鼠肾脏的成纤维细胞系中的生长。

Nature. 1962 Apr 21;194:253-5. doi: 10.1038/194253a0.

Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence.仓鼠细胞克隆的多瘤病毒转化——对影响细胞感受态的遗传因素的研究

Virology. 1962 Feb;16:147-51. doi: 10.1016/0042-6822(62)90290-8.

Attenuated strains of the virus of foot-and-mouth disease. Studies in small animals with strains of common origin modified by different methods.口蹄疫病毒减毒株。对经不同方法改良的同源毒株在小动物身上进行的研究。

Arch Gesamte Virusforsch. 1963;12:472-86. doi: 10.1007/BF01242155.

Use of BHK 21 cells in the preparation of mouse attenuated live foot-and-mouth disease vaccines for the immunization of cattle.使用BHK 21细胞制备用于牛免疫的小鼠减毒活口蹄疫疫苗。

Nature. 1962 Nov 17;196:655-6. doi: 10.1038/196655a0.

Studies on rabbit-adapted foot-and-mouth disease virus. I. Propagation and pathogenicity.兔适应口蹄疫病毒的研究。I. 增殖与致病性。

Am J Vet Res. 1959 Jan;20:133-7.

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