通过抑制巨噬细胞迁移检测到的肿瘤特异性抗原
Tumor-specific antigens detected by inhibition of macrophage migration.
作者信息
Kronman B S, Wepsic H T, Churchill W H, Zbar B, Borsos T, Rapp H J
出版信息
Science. 1969 Jul 18;165(3890):296-7. doi: 10.1126/science.165.3890.296.
PMID:4306915
Abstract
Tumor-specific antigens of a guinea pig hepatoma induced by diethylnitrosamine were detected by the inhibition of migration of specifically sensitized macrophages from capillary tubes, and by the local passive transfer of delayed skin hypersensitivity and the suppression of growth of intradermally same injected tumor.
摘要
通过抑制特异性致敏巨噬细胞从毛细管的迁移、局部被动转移迟发型皮肤超敏反应以及抑制皮内注射相同肿瘤的生长，检测了二乙基亚硝胺诱导的豚鼠肝癌的肿瘤特异性抗原。
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