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通过抑制巨噬细胞迁移检测到的肿瘤特异性抗原

Tumor-specific antigens detected by inhibition of macrophage migration.

作者信息

Kronman B S, Wepsic H T, Churchill W H, Zbar B, Borsos T, Rapp H J

出版信息

Science. 1969 Jul 18;165(3890):296-7. doi: 10.1126/science.165.3890.296.

DOI:10.1126/science.165.3890.296
PMID:4306915
Abstract

Tumor-specific antigens of a guinea pig hepatoma induced by diethylnitrosamine were detected by the inhibition of migration of specifically sensitized macrophages from capillary tubes, and by the local passive transfer of delayed skin hypersensitivity and the suppression of growth of intradermally same injected tumor.

摘要

通过抑制特异性致敏巨噬细胞从毛细管的迁移、局部被动转移迟发型皮肤超敏反应以及抑制皮内注射相同肿瘤的生长，检测了二乙基亚硝胺诱导的豚鼠肝癌的肿瘤特异性抗原。

相似文献

1
Tumor-specific antigens detected by inhibition of macrophage migration.通过抑制巨噬细胞迁移检测到的肿瘤特异性抗原
Science. 1969 Jul 18;165(3890):296-7. doi: 10.1126/science.165.3890.296.
2
Tumor-specific antigens: detection by local transfer of delayed skin hypersensitivity.
J Natl Cancer Inst. 1969 Oct;43(4):869-75.
3
Immunologic rejection of diethylnitrosamine-induced hepatomas in strain 2 guinea pigs: participation of basophilic leukocytes and macrophage aggregates.2系豚鼠中二乙基亚硝胺诱导的肝癌的免疫排斥反应：嗜碱性白细胞和巨噬细胞聚集体的参与
J Exp Med. 1973 Mar 1;137(3):751-75. doi: 10.1084/jem.137.3.751.
4
Antigenic specificity of hepatomas induced in strain-2 guinea pigs by diethylnitrosamine.
J Natl Cancer Inst. 1969 Oct;43(4):833-41.
5
Detection of antigens of a new diethylnitrosamine-induced transplantable hepatoma by delayed hypersensitivity.通过迟发型超敏反应检测新型二乙基亚硝胺诱导的可移植性肝癌的抗原
J Natl Cancer Inst. 1968 Jul;41(1):13-29.
6
Transfer of tumor-specific delayed hypersensitivity in vitro to normal guinea pig peritoneal exudate cells using RNA extracts from sensitized lymphoid tissues.利用致敏淋巴组织的RNA提取物在体外将肿瘤特异性迟发型超敏反应转移至正常豚鼠腹腔渗出细胞。
Cancer Res. 1973 Dec;33(12):3165-71.
7
Detection of cellular immunity to tumor antigens of a guinea pig hepatoma by inhibition of macrophage migration.通过抑制巨噬细胞迁移检测豚鼠肝癌肿瘤抗原的细胞免疫
J Natl Cancer Inst. 1972 Feb;48(2):541-9.
8
Tumor immunity: tumor suppression in vivo initiated by soluble products of specifically stimulated lymphocytes.肿瘤免疫：由特异性刺激淋巴细胞的可溶性产物在体内引发的肿瘤抑制。
Science. 1971 May 14;172(3984):729-31. doi: 10.1126/science.172.3984.729.
9
Antigenicity of a new diethylnitrosamine-induced transplantable guinea pig hepatoma: pathology and formation of ascites variant.一种新的二乙基亚硝胺诱导的可移植性豚鼠肝癌的抗原性：腹水变异型的病理学及形成
J Natl Cancer Inst. 1968 Jul;41(1):1-7.
10
Macrophage-bound antigens. II. Comparison of the immunogenicity of antigens bound to macrophages, lymphocytes, thymocytes and hepatoma cells.巨噬细胞结合抗原。II. 与巨噬细胞、淋巴细胞、胸腺细胞及肝癌细胞结合的抗原的免疫原性比较
J Immunol. 1972 Aug;109(2):255-61.

引用本文的文献

1
Demonstration of delayed hypersensitivity to soluble antigens of chemically induced tumors by inhibition of macrophage migration.通过抑制巨噬细胞迁移来证明对化学诱导肿瘤的可溶性抗原的迟发型超敏反应。
Proc Natl Acad Sci U S A. 1969 Dec;64(4):1176-80. doi: 10.1073/pnas.64.4.1176.
2
Separation of lymphocytes and macrophages from suspensions of guinea pig peritonitis exudate cells using programmed gradient sedimentation.使用程序梯度沉降法从豚鼠腹膜炎渗出细胞悬液中分离淋巴细胞和巨噬细胞。
Am J Pathol. 1971 May;63(2):255-76.
3
Production of macrophage migration inhibition factor by continuous cell lines.
连续细胞系产生巨噬细胞移动抑制因子。
J Exp Med. 1972 Feb 1;135(2):255-66. doi: 10.1084/jem.135.2.255.
4
In vitro delayed hypersensitivity in normal and hyporeactive patients.正常及反应低下患者的体外迟发型超敏反应
Immunology. 1971 May;20(5):641-8.
5
Evaluation of leucocyte functions six years after tumour autograft in human mammary cancer.人乳腺癌肿瘤自体移植六年后白细胞功能的评估。
Br J Cancer Suppl. 1973 Aug;1:83-96.
6
Cellular immunity to breast carcinoma and malignant melanoma.对乳腺癌和恶性黑色素瘤的细胞免疫。
Br J Cancer Suppl. 1973 Aug;1:77-82.
7
The biological activities of soluble lymphocyte products.可溶性淋巴细胞产物的生物学活性。
Clin Exp Immunol. 1972 Jan;10(1):1-23.
8
Comparison of antigenicity of hepatoma cells, normal liver cells, foetal liver cells and chemically damaged liver cells in guinea-pigs immunized with hepatomata using the macrophage migration inhibition test.用巨噬细胞游走抑制试验比较用肝癌免疫的豚鼠中肝癌细胞、正常肝细胞、胎儿肝细胞及化学损伤肝细胞的抗原性。
Br J Cancer. 1974 Aug;30(2):109-7. doi: 10.1038/bjc.1974.121.
9
Immunologic rejection of diethylnitrosamine-induced hepatomas in strain 2 guinea pigs: participation of basophilic leukocytes and macrophage aggregates.2系豚鼠中二乙基亚硝胺诱导的肝癌的免疫排斥反应：嗜碱性白细胞和巨噬细胞聚集体的参与
J Exp Med. 1973 Mar 1;137(3):751-75. doi: 10.1084/jem.137.3.751.
10
[Immunology of cancer].[癌症免疫学]
Langenbecks Arch Chir. 1971 Dec;329:264-75. doi: 10.1007/BF01770521.