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[眼内寄生虫病(眼内蝇蛆病)患者房水中IgE的测定(作者译)]

[The determination of IgE in human aqueous humor in a case of intraocular parasitosis (ophthalmomviasis interna) (author's transl)].

作者信息

Hartmann C H, Haut J

出版信息

Klin Monbl Augenheilkd. 1979 Jan;174(1):73-81.

PMID:431026
Abstract

A case of intraocular myasis is here reported, as well as the difficulties of diagnosis--mostly too late--of this disease, which is rare in Europe and the northern hemisphere and which leads, almost invariably, to functional or even anatomical loss of the eye.--The determination of IgE in human aqueous humor (ah) and corresponding serum (s) by means of the ultrasensitive and quite simple PRIST method could represent a possibility of timely diagnosis, and this theoretically too in the case of other, much more frequent oculoparasitosis cases.--A retrospective study of the preoperative aqueous humor of the ophthalmomyiasis case presented here revealed an IgE concentration of 113 U/ml in the aqueous humor, with only 3 U/ml (1 U congruent to 2 ng) in the corresponding serum. A simple serum-IgES-determination would not have permitted the diagnosis--at least not in the case examined--just as little as numeration of eosinophilic granulocytes in blood and/or aqueous humor.

摘要

本文报告了一例眼内蝇蛆病病例,以及该疾病诊断的困难——大多为时已晚——这种疾病在欧洲和北半球较为罕见,几乎总会导致眼睛功能甚至结构丧失。——通过超灵敏且相当简单的PRIST方法测定人房水(ah)和相应血清(s)中的IgE,可能代表了一种及时诊断的可能性,理论上在其他更常见的眼寄生虫病病例中也是如此。——对本文呈现的眼蝇蛆病病例术前房水进行的回顾性研究显示,房水中IgE浓度为113 U/ml,而相应血清中仅为3 U/ml(1 U相当于2 ng)。简单的血清IgE测定无法做出诊断——至少在所检查的病例中不行——就如同对血液和/或房水中嗜酸性粒细胞进行计数一样。

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