猿猴病毒40诱导的T抗原和肿瘤抗原。
Simian virus 40-induced T and tumor antigens.
作者信息
Potter C W, McLaughlin B C, Oxford J S
出版信息
J Virol. 1969 Nov;4(5):574-9. doi: 10.1128/JVI.4.5.574-579.1969.
Abstract
Antigen extracts from simian virus 40 (SV40) transplanted hamster tumors were studied by rate-zonal centrifugation. Three species or molecular forms of antigen were demonstrated. The major antigen component corresponded to a molecular weight of 65,000 to 75,000, and two larger species were detectable in smaller quantities. Similar studies were carried out on SV40 virus-induced T antigen from BSC-1 cells. Three antigen components were again detected. Quantitative differences in the expression of "T" and tumor antigen species were reproducibly found.
摘要
通过速率区带离心法研究了从猿猴病毒40（SV40）移植的仓鼠肿瘤中提取的抗原。证明了三种抗原种类或分子形式。主要抗原成分的分子量为65,000至75,000，另外两种较大的种类可少量检测到。对来自BSC-1细胞的SV40病毒诱导的T抗原进行了类似研究。再次检测到三种抗原成分。可重复地发现“T”抗原和肿瘤抗原种类表达的定量差异。
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