• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Heterocyclic thiosemicarbazones: correlation between structure, inhibition of ribonucleotide reductase, and inhibition of DNA viruses.

作者信息

Brockman R W, Sidwell R W, Arnett G, Shaddix S

出版信息

Proc Soc Exp Biol Med. 1970 Feb;133(2):609-14. doi: 10.3181/00379727-133-34528.

DOI:10.3181/00379727-133-34528
PMID:4313146
Abstract
摘要

相似文献

1
Heterocyclic thiosemicarbazones: correlation between structure, inhibition of ribonucleotide reductase, and inhibition of DNA viruses.杂环硫代氨基脲：结构、核糖核苷酸还原酶抑制作用与DNA病毒抑制作用之间的相关性
Proc Soc Exp Biol Med. 1970 Feb;133(2):609-14. doi: 10.3181/00379727-133-34528.
2
Inhibition of the replication of DNA viruses by phosphonylmethoxyalkyl-purines and -pyrimidines.
J Chemother. 1989 Jul;1(4 Suppl):1074-6.
3
Antiviral effect of daunomycin.柔红霉素的抗病毒作用。
Nature. 1969 Apr 5;222(5188):36-8. doi: 10.1038/222036a0.
4
Thiosemicarbazones of 2-acetylpyridine, 2-acetylquinoline, 1-acetylisoquinoline, and related compounds as inhibitors of herpes simplex virus in vitro and in a cutaneous herpes guinea pig model.2-乙酰吡啶、2-乙酰喹啉、1-乙酰异喹啉及其相关化合物的硫代氨基脲作为单纯疱疹病毒的体外抑制剂及在豚鼠皮肤疱疹模型中的作用
Antiviral Res. 1986 Jul;6(4):197-222. doi: 10.1016/0166-3542(86)90002-1.
5
Potentiation of antiherpetic activity of acyclovir by ribonucleotide reductase inhibition.通过抑制核糖核苷酸还原酶增强阿昔洛韦的抗疱疹病毒活性。
Proc Natl Acad Sci U S A. 1985 Jun;82(12):4254-7. doi: 10.1073/pnas.82.12.4254.
6
Purine analogs as potential anticytomegalovirus agents.嘌呤类似物作为潜在的抗巨细胞病毒药物。
Proc Soc Exp Biol Med. 1969 Sep;131(4):1223-30. doi: 10.3181/00379727-131-34075.
7
Selective inhibition of herpes simplex virus ribonucleoside diphosphate reductase by derivatives of 2-acetylpyridine thiosemicarbazone.
Biochem Pharmacol. 1986 May 1;35(9):1539-45. doi: 10.1016/0006-2952(86)90122-x.
8
The effect of isatin beta-thiosemicarbazone derivatives on vaccinia virus multiplication in L-132 cell line (human embryonic lung).异吲哚酮β-硫代半卡巴腙衍生物对痘苗病毒在L-132细胞系（人胚肺）中增殖的影响。
Acta Microbiol Pol A. 1973;5(3):199-204.
9
Inhibition of cytomegalovirus by rifampin.利福平对巨细胞病毒的抑制作用。
J Infect Dis. 1972 May;125(5):552-5. doi: 10.1093/infdis/125.5.552.
10
Inhibition of arc-like fragments and immature forms of vaccinia virus by methisazone.甲吲噻腙对痘苗病毒弧形片段和未成熟形式的抑制作用。
Proc Soc Exp Biol Med. 1972 Feb;139(2):558-61. doi: 10.3181/00379727-139-36185.

引用本文的文献

1
Synthesis, Characterization, and Anticancer Activity of Phosphanegold(i) Complexes of 3-Thiosemicarbano-butan-2-one Oxime.3-硫代氨基甲酰基丁-2-酮肟的膦金（I）配合物的合成、表征及抗癌活性
Biomedicines. 2023 Sep 12;11(9):2512. doi: 10.3390/biomedicines11092512.
2
Design, synthesis, molecular modelling and antitumor evaluation of -glucosylated rhodanines through topo II inhibition and DNA intercalation.通过拓扑异构酶 II 抑制和 DNA 嵌入设计、合成、分子模拟及-葡糖苷化罗丹宁类化合物的抗肿瘤活性评价。
J Enzyme Inhib Med Chem. 2023 Dec;38(1):2163996. doi: 10.1080/14756366.2022.2163996.
3
Molecular docking, PASS analysis, bioactivity score prediction, synthesis, characterization and biological activity evaluation of a functionalized 2-butanone thiosemicarbazone ligand and its complexes.
一种功能化的2-丁酮硫代半卡巴腙配体及其配合物的分子对接、PASS分析、生物活性评分预测、合成、表征和生物活性评价
J Chem Biol. 2017 Apr 4;10(3):91-104. doi: 10.1007/s12154-017-0167-y. eCollection 2017 Jul.
4
Inactivation of herpes simplex virus by thiosemicarbazones and certain cations.硫代卡巴腙和某些阳离子对单纯疱疹病毒的灭活作用。
Antimicrob Agents Chemother. 1974 Apr;5(4):398-402. doi: 10.1128/AAC.5.4.398.
5
Antiviral activity of 2-acetylpyridine thiosemicarbazones against herpes simplex virus.2-乙酰基吡啶硫代半卡巴腙对单纯疱疹病毒的抗病毒活性
Antimicrob Agents Chemother. 1981 Apr;19(4):682-5. doi: 10.1128/AAC.19.4.682.
6
Preferential inhibition of ribonucleic acid synthesis by a new thiosemicarbazone possessing antibacterial and antiparasitic properties.一种具有抗菌和抗寄生虫特性的新型硫代卡巴腙对核糖核酸合成的优先抑制作用。
Antimicrob Agents Chemother. 1981 Feb;19(2):234-7. doi: 10.1128/AAC.19.2.234.
7
Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir.单纯疱疹病毒核糖核苷酸还原酶突变体对阿昔洛韦高度敏感。
Antimicrob Agents Chemother. 1989 Aug;33(8):1395-9. doi: 10.1128/AAC.33.8.1395.