一种具有抗菌和抗寄生虫特性的新型硫代卡巴腙对核糖核酸合成的优先抑制作用。
Preferential inhibition of ribonucleic acid synthesis by a new thiosemicarbazone possessing antibacterial and antiparasitic properties.
作者信息
Brown R E, Stancato F A, Wolfe A D
出版信息
Antimicrob Agents Chemother. 1981 Feb;19(2):234-7. doi: 10.1128/AAC.19.2.234.
Abstract
We determined the influence of the azacycloheptane derivative (H) of a 2-acetylpyridine thiosemicarbazone on growth and macromolecular synthesis in Escherichia coli AT-9. Thiosemicarbazone H caused bacteriostasis and a primary inhibition of ribonucleic acid synthesis; secondary effects included inhibition of deoxyribonucleic acid and protein synthesis. Addition of cooper or other transition elements was not necessary for these inhibitions.
摘要
我们测定了2-乙酰吡啶硫代半卡巴腙的氮杂环庚烷衍生物（H）对大肠杆菌AT-9生长和大分子合成的影响。硫代半卡巴腙H引起抑菌作用，并对核糖核酸合成产生初步抑制；次要影响包括对脱氧核糖核酸和蛋白质合成的抑制。这些抑制作用无需添加铜或其他过渡元素。
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1
Preferential inhibition of ribonucleic acid synthesis by a new thiosemicarbazone possessing antibacterial and antiparasitic properties.一种具有抗菌和抗寄生虫特性的新型硫代卡巴腙对核糖核酸合成的优先抑制作用。
Antimicrob Agents Chemother. 1981 Feb;19(2):234-7. doi: 10.1128/AAC.19.2.234.
2
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6
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本文引用的文献
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