Fortin-Magana R, Hurwitz R, Herbst J J, Kretchmer N
Science. 1970 Mar 20;167(3925):1627-8. doi: 10.1126/science.167.3925.1627.
Some intestinal enZymes were assayed which were related to: (i) Cellular proliferation, for example, aspartate carbamoyltransferase, thymidine kinase, uridine kinase, and dihydroorotase; (ii) cellular differentiation, for example, lactase, invertase, maltase, alkaline phosphatase, and dipeptidase; and (iii) lysosomes, for example, beta-glucuronidase, acid beta-galactosidase, and acid phosphatase. These enzymatic determinations can be used to distinguish the crypt from the villus during healthy or diseased states.
(i) 细胞增殖，例如天冬氨酸氨甲酰转移酶、胸苷激酶、尿苷激酶和二氢乳清酸酶；(ii) 细胞分化，例如乳糖酶、转化酶、麦芽糖酶、碱性磷酸酶和二肽酶；以及(iii) 溶酶体，例如β-葡萄糖醛酸酶、酸性β-半乳糖苷酶和酸性磷酸酶。这些酶活性测定可用于在健康或患病状态下区分隐窝和绒毛。
