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小肠黏膜线粒体中一种NAD(P)+依赖的“苹果酸”酶的鉴定。

Identification of an NAD(P)+-dependent 'malic' enzyme in small-intestinal-mucosal mitochondria.

作者信息

Sauer L A, Dauchy R T, Nagel W O

出版信息

Biochem J. 1979 Oct 15;184(1):185-8. doi: 10.1042/bj1840185.

Abstract

An NAD(P)+-dependent 'malic' enzyme is shown to be present in mitochondria from small-intestinal mucosa. The intracellular location, activity and regulatory kinetic properties of the enzyme suggest that it participates in the major energy-producing pathway for net oxidation of glutamine-derived tricarboxylic acid-cycle intermediates.

摘要

一种依赖烟酰胺腺嘌呤二核苷酸(磷酸)(NAD(P)+)的“苹果酸”酶被证明存在于小肠黏膜的线粒体中。该酶的细胞内定位、活性及调节动力学特性表明,它参与了谷氨酰胺衍生的三羧酸循环中间产物净氧化的主要能量产生途径。

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