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血管加压素：对集合管细胞尿表面可变形性的影响。

Vasopressin: effect on deformability of urinary surface of collecting duct cells.

作者信息

Grantham J J

出版信息

Science. 1970 May 29;168(3935):1093-5. doi: 10.1126/science.168.3935.1093.

DOI:10.1126/science.168.3935.1093
PMID:4315087
Abstract

In isolated renal collecting ducts vasopressin decreased the negative pressure required to suck a hemispherical bulge of the epitheliat cells' urinary surface into the tip of a micropipette. Increased surface deformability may be related to the increased permeability to water which also occurs in the apex of the cells in response to the hormone.

摘要

在离体肾集合管中，血管加压素降低了将上皮细胞尿表面的半球形凸起吸入微吸管尖端所需的负压。表面可变形性增加可能与水通透性增加有关，水通透性增加也发生在细胞顶端以响应该激素。

相似文献

1
Vasopressin: effect on deformability of urinary surface of collecting duct cells.血管加压素：对集合管细胞尿表面可变形性的影响。
Science. 1970 May 29;168(3935):1093-5. doi: 10.1126/science.168.3935.1093.
2
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Urinary concentrating defect of adrenal insufficiency. Permissive role of adrenal steroids on the hydroosmotic response across the rabbit cortical collecting tubule.肾上腺皮质功能不全的尿浓缩功能缺陷。肾上腺类固醇对家兔皮质集合管水渗透反应的允许作用。
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Inhibition by lithium of the hydroosmotic action of vasopressin in the isolated perfused cortical collecting tubule of the rabbit.锂对家兔离体灌注皮质集合管中血管升压素水渗透作用的抑制
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Functional profile of the isolated uremic nephron. Impaired water permeability and adenylate cyclase responsiveness of the cortical collecting tubule to vasopressin.孤立尿毒症肾单位的功能特征。皮质集合管对血管加压素的水通透性和腺苷酸环化酶反应性受损。
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Quinidine effect on hydrosmotic response of collecting tubules to vasopressin and cAMP.奎尼丁对集合管水渗透性反应、抗利尿激素及环磷酸腺苷的影响。
Am J Physiol. 1987 Jun;252(6 Pt 2):F1103-11. doi: 10.1152/ajprenal.1987.252.6.F1103.
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cAMP-dependent protein kinase mediates hydrosmotic effect of vasopressin in collecting duct.环磷酸腺苷（cAMP）依赖性蛋白激酶介导抗利尿激素在集合管中的渗透效应。
Am J Physiol. 1992 Jul;263(1 Pt 1):C147-53. doi: 10.1152/ajpcell.1992.263.1.C147.

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