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Radioreceptor assay of adrenocorticotropic hormone: new approach to assay of polypeptide hormones in plasma.

作者信息

Lefkowitz R J, Roth J, Pastan I

出版信息

Science. 1970 Nov 6;170(3958):633-5. doi: 10.1126/science.170.3958.633.

DOI:10.1126/science.170.3958.633
PMID:4319388
Abstract

Biologically active iodine-125-labeled adrenocorticotropic hormone (ACTH) binds specifically to ACTH receptors extracted from adrenals. Unlabeled ACTH at 1 picogram per milliliter significantly displaces labeled ACTH from these receptors. This system, which appears to be applicable to all polypeptide hormones, provides a rapid and sensitive method for measurements of biologically active ACTH in dilute whole plasma.

摘要

相似文献

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Radioreceptor assay of adrenocorticotropic hormone: new approach to assay of polypeptide hormones in plasma.
Science. 1970 Nov 6;170(3958):633-5. doi: 10.1126/science.170.3958.633.
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A sensitive radioimmunoassay for plasma ACTH levels.一种用于检测血浆促肾上腺皮质激素（ACTH）水平的灵敏放射免疫测定法。
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[ACTH].促肾上腺皮质激素
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5
A sensitive bioassay for the determination of human plasma ACTH levels.
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A new phenomenon of usefulness in the radioimmunoassay of plasma adrenocorticotropic hormone.
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[On serum ACTH].[关于血清促肾上腺皮质激素（ACTH）]
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[Radioimmunoassay of ACTH].
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Radioimmunoassay of ACTH in plasma.血浆促肾上腺皮质激素的放射免疫测定
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Methodological problems and clinical validity of an ACTH radioimmunoassay method applied to extracted plasma samples.应用于提取血浆样本的促肾上腺皮质激素放射免疫分析方法的方法学问题及临床有效性
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