Synthesis of some newer piperazinoquinazolones as cardiovascular agents.
作者信息
Dubey M, Verma V K, Shanker K, Sinha J N, Bhargava K P, Kishor K
出版信息
Pharmazie. 1979 Jan;34(1):18-20. doi: 10.1002/chin.197919284.
PMID:432250
Abstract
Twenty nine new substituted 2-methyl-3-(gamma-piperazino-propiophenyl)-4-quinazolone hydrochlorides were synthesised by the Mannich reaction of substituted quinazolones with substituted piperazines and evaluated for their cardiovascular activity. Several compounds of the series exhibited marked and sustained hypotensive activity.
摘要
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