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迷走神经支配的青蛙缝匠肌的收缩和电反应。

Contractile and electrical responses of vagus-innervated frog sartorius muscles.

作者信息

Landmesser L

出版信息

J Physiol. 1971 Mar;213(3):707-25. doi: 10.1113/jphysiol.1971.sp009410.

Abstract
  1. Frog sartorius muscles were transplanted to the thoracic region and re-innervated by the gastric vagus nerve. Contractile responses of the re-innervated muscles were studied. Micro-electrodes were used to measure electrical properties of the muscle fibre membrane. Histological studies of the sartorius and vagus nerves and re-innervated muscles were also carried out.2. Autonomic nerve fibres of the gastric vagus form functional connexions with the skeletal muscle fibres. Such vagus-innervated muscle fibres do not atrophy.3. Neither the contractile nor the passive electrical properties of the muscle fibres are altered by vagal innervation.4. Synaptic transmission is quantal in nature and describable by a Poisson distribution as at normal sartorius junctions. The muscle fibres, however, do show extensive multiple-innervation, and unlike normal sartorius junctions, vagus-muscle junctions have a low quantal content and show a long-lasting facilitation.5. Properties of the vagus nerve fibres apparently are not altered by synapsing with skeletal muscle fibres. They remain small diameter and have high threshold for electrical stimulation.6. The ability of these nerve and muscle fibres to influence each other is rather limited in the adult amphibian.
摘要
  1. 将青蛙的缝匠肌移植到胸部区域,并由胃迷走神经重新支配。对重新支配的肌肉的收缩反应进行了研究。使用微电极测量肌纤维膜的电特性。还对缝匠肌、迷走神经和重新支配的肌肉进行了组织学研究。

  2. 胃迷走神经的自主神经纤维与骨骼肌纤维形成功能性连接。这种由迷走神经支配的肌纤维不会萎缩。

  3. 迷走神经支配不会改变肌纤维的收缩特性和被动电特性。

  4. 突触传递本质上是量子化的,并且如在正常缝匠肌连接处一样,可用泊松分布来描述。然而,肌纤维确实表现出广泛的多重支配,并且与正常缝匠肌连接处不同,迷走神经 - 肌肉连接处的量子含量低且表现出持久的易化作用。

  5. 迷走神经纤维的特性显然不会因与骨骼肌纤维形成突触而改变。它们的直径仍然较小,并且对电刺激具有高阈值。

  6. 在成年两栖动物中,这些神经纤维和肌纤维相互影响的能力相当有限。

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The union of different kinds of nerve fibres.不同种类神经纤维的联合。
J Physiol. 1904 Aug 22;31(5):365-91. doi: 10.1113/jphysiol.1904.sp001042.

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