血管紧张素和去甲肾上腺素对猫和犬颈交感神经纤维放电的影响。
Effects of angiotensin and noradrenaline on discharge in fibres of the cervical sympathetic nerve in cats and dogs.
作者信息
Morrison J F, Pickford M
出版信息
Br J Pharmacol. 1971 Apr;41(4):674-82. doi: 10.1111/j.1476-5381.1971.tb07075.x.
Abstract
- The effects of angiotensin and noradrenaline on discharge frequency in single and few-fibre preparations of the cervical sympathetic nerve of cats and dogs have been compared.2. When equal changes in blood pressure were produced by intravenous infusion of these drugs, the changes found in sympathetic discharge were similar both in anaesthetized animals and in a decerebrate one.3. Angiotensin and noradrenaline also have similar effects on discharge in sympathetic nerve fibres following complete denervation of the baroreceptor and chemoreceptor nerves.4. It is concluded that when the blood pressure is raised to 200 mmHg by angiotensin, the drug has no central stimulant action on the sympathetic nervous system.
摘要
已比较了血管紧张素和去甲肾上腺素对猫和狗颈交感神经单纤维及少纤维标本放电频率的影响。
当通过静脉输注这些药物使血压产生同等变化时，在麻醉动物和去大脑动物中发现的交感神经放电变化相似。
对压力感受器和化学感受器神经完全去神经支配后，血管紧张素和去甲肾上腺素对交感神经纤维放电也有相似作用。
得出的结论是，当血管紧张素使血压升至200 mmHg时，该药物对交感神经系统无中枢兴奋作用。
相似文献
1
Effects of angiotensin and noradrenaline on discharge in fibres of the cervical sympathetic nerve in cats and dogs.血管紧张素和去甲肾上腺素对猫和犬颈交感神经纤维放电的影响。
Br J Pharmacol. 1971 Apr;41(4):674-82. doi: 10.1111/j.1476-5381.1971.tb07075.x.
2
Sex differences in the changes in sympathetic nerve activity when arterial pressure is raised by infusion of angiotensin and noradrenaline.通过输注血管紧张素和去甲肾上腺素升高动脉压时交感神经活动变化中的性别差异。
J Physiol. 1971 Jul;216(1):69-85. doi: 10.1113/jphysiol.1971.sp009509.
3
Pressure-independent inhibition of sympathetic activity by noradrenaline: role of baroreceptor C fibres.去甲肾上腺素对交感神经活动的压力非依赖性抑制作用：压力感受器C纤维的作用
Acta Physiol Scand. 1977 Jul;100(3):303-8. doi: 10.1111/j.1748-1716.1977.tb05954.x.
4
Digoxin toxicity: primary sites of drug action on the sympathetic nervous system.地高辛毒性：药物对交感神经系统的主要作用部位。
J Pharmacol Exp Ther. 1976 Apr;197(1):1-9.
5
Contribution of baroreceptor reflexes to blood pressure and sympathetic responses to cholecystokinin and vasoactive intestinal peptide in anesthetized dogs.压力感受器反射对麻醉犬血压及对胆囊收缩素和血管活性肠肽的交感反应的作用。
Eur J Pharmacol. 1990 Jan 17;175(3):245-51. doi: 10.1016/0014-2999(90)90561-j.
6
The effects of propanidid on arterial pressure, pulse rate, preganglionic sympathetic activity and barostatic reflexes in the cat.丙泮尼地对猫的动脉血压、脉搏率、节前交感神经活动及压力反射的影响
Can Anaesth Soc J. 1977 Jul;24(4):505-13. doi: 10.1007/BF03005455.
7
The contribution of the arterial chemoreceptors to the stimulation of respiration by adrenaline and noradrenaline in the cat.猫的动脉化学感受器对肾上腺素和去甲肾上腺素刺激呼吸的作用。
J Physiol. 1968 Jul;197(1):1-23. doi: 10.1113/jphysiol.1968.sp008541.
8
Inhibition by angiotensin II of baroreceptor-evoked activity in cardiac vagal efferent nerves in the dog.血管紧张素II对犬心脏迷走神经传入神经中压力感受器诱发活动的抑制作用。
J Physiol. 1979 Sep;294:69-80. doi: 10.1113/jphysiol.1979.sp012915.
9
The effect of atenolol on the spontaneous and reflex activity of the sympathetic nerves in the cat: influence of cardiopulmonary receptors.阿替洛尔对猫交感神经自发活动和反射活动的影响：心肺感受器的作用
Br J Pharmacol. 1983 Feb;78(2):425-31. doi: 10.1111/j.1476-5381.1983.tb09407.x.
10
Facilitation of cardiac sympathetic function by angiotensin II: role of presynaptic angiotensin receptors.血管紧张素II对心脏交感神经功能的促进作用：突触前血管紧张素受体的作用
Eur J Pharmacol. 1978 Dec 1;52(3-4):405-9. doi: 10.1016/0014-2999(78)90299-6.
引用本文的文献
1
[Relationship between the renin-angiotensin system and the autonomic nervous system].肾素-血管紧张素系统与自主神经系统之间的关系
Klin Wochenschr. 1972 Dec 1;50(23):1069-81. doi: 10.1007/BF01486850.
2
Sex differences in the changes in sympathetic nerve activity when arterial pressure is raised by infusion of angiotensin and noradrenaline.通过输注血管紧张素和去甲肾上腺素升高动脉压时交感神经活动变化中的性别差异。
J Physiol. 1971 Jul;216(1):69-85. doi: 10.1113/jphysiol.1971.sp009509.
本文引用的文献
1
Discharges in mammalian sympathetic nerves.哺乳动物交感神经中的放电。
J Physiol. 1932 Feb 8;74(2):115-33. doi: 10.1113/jphysiol.1932.sp002832.
2
The mechanism of adrenaline-induced inhibition of sympathetic preganglionic activity.肾上腺素诱导的交感神经节前活动抑制机制。
J Physiol. 1962 Apr;161(1):62-72. doi: 10.1113/jphysiol.1962.sp006873.
3
Central effects of peptides on the cardiovascular system.肽对心血管系统的中枢效应。
Ann N Y Acad Sci. 1963 Feb 4;104:299-311. doi: 10.1111/j.1749-6632.1963.tb17675.x.
4
Preganglionic sympathetic activity in normal and in reserpine-treated cats.正常猫和利血平处理猫的节前交感神经活动
J Physiol. 1960 Jan;150(1):114-33. doi: 10.1113/jphysiol.1960.sp006377.
5
On the pharmacology of synthetic hypertensine.论合成高血压素的药理学
Arch Int Pharmacodyn Ther. 1960 Feb 1;124:21-44.
6
Spontaneous activity of sympathetic preganglionic neurons.交感神经节前神经元的自发活动。
Can J Physiol Pharmacol. 1968 Nov;46(6):887-96. doi: 10.1139/y68-138.
7
Studies upon the relationship between baroreceptor and sympathetic activity.压力感受器与交感神经活动之间关系的研究。
Q J Exp Physiol Cogn Med Sci. 1968 Jan;53(1):23-32. doi: 10.1113/expphysiol.1968.sp001942.
8
Cardiovascular effects of angiotensin mediated by the central nervous system of the rabbit.血管紧张素经家兔中枢神经系统介导产生的心血管效应。
Cardiovasc Res. 1970 Jan;4(1):36-43. doi: 10.1093/cvr/4.1.36.
9
Central pressor effect of angiotensin mediated by the parasympathetic nervous system.由副交感神经系统介导的血管紧张素的中枢升压作用。
Nature. 1968 Dec 28;220(5174):1331-2. doi: 10.1038/2201331a0.
10
Effect of angiotensin on sympathetic nerve activity.血管紧张素对交感神经活动的影响。
Acta Physiol Scand. 1968 Sep-Oct;74(1):134-41. doi: 10.1111/j.1748-1716.1968.tb04222.x.
Zotero 插件