服用双硫仑后出现的周围神经病变。
Peripheral neuropathy after disulfiram administration.
作者信息
Gardner-Thorpe C, Benjamin S
出版信息
J Neurol Neurosurg Psychiatry. 1971 Jun;34(3):253-9. doi: 10.1136/jnnp.34.3.253.
Abstract
Peripheral neuropathy and optic neuritis occurring in alcoholics are sometimes due to the toxic effects of disulfiram rather than to alcohol. Unless this is considered in the management of such patients it is likely that administration of the drug will be continued. In the past there have been reports of 16 cases of peripheral neuropathy and six cases of optic neuritis, possibly caused in this way; these reports are reviewed and a further six cases are described. The effects of disulfiram on the nervous system are briefly discussed.
摘要
酗酒者出现的周围神经病变和视神经炎有时是由于双硫仑的毒性作用而非酒精所致。除非在这类患者的治疗中考虑到这一点，否则很可能会继续使用该药物。过去曾有报告称16例周围神经病变和6例视神经炎可能是由此引起的；本文对这些报告进行了回顾，并描述了另外6例病例。文中还简要讨论了双硫仑对神经系统的影响。
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