Zhdanov V M, Elder J H, Lerner R, Ivanova V T, Iamnikova S S
Vopr Virusol. 1979 Mar-Apr(2):109-15.
A comparative study of peptide maps of major proteins of hemagglutinin, nucleoprotein, membrane of influenza A virus strains A/WS/33, A/FM/1/47, A/Singapore/1/57, A/USSR/090/77, A/Port Chalmers/1/73 (MRC-11), was carried out. The greatest differences were observed in the peptide maps of heavy and light chains of hemagglutinin of different serotypes. The peptide maps of nucleoprotein and membrane were more similar. The A/USSR/090/77 strain by peptide maps was close to but not identical with the A/FM/1/47 strain. Structural polypeptides of the virion separated by SDS-polyacrylamide gel electrophoresis may be used satisfactorily for comparative studies of influenza virus peptide maps.
对甲型流感病毒株A/WS/33、A/FM/1/47、A/新加坡/1/57、A/苏联/090/77、A/查尔默斯港/1/73(MRC - 11)的血凝素、核蛋白、膜的主要蛋白质的肽图进行了比较研究。在不同血清型血凝素的重链和轻链的肽图中观察到最大差异。核蛋白和膜的肽图更相似。通过肽图,A/苏联/090/77株与A/FM/1/47株相近但不相同。通过SDS - 聚丙烯酰胺凝胶电泳分离的病毒粒子的结构多肽可令人满意地用于流感病毒肽图的比较研究。