Sokolov B P
Vopr Virusol. 1980 Sep-Oct(5):553-4.
A comparative study of protein of nucleoproteins (NP-protein) of influenza A viruses by peptide mapping shows its variability to be small within one drifting series and quite marked in strains belonging to different sero-types. In oligopeptide maps of NP-proteins of viruses of the Hong Kong (H3N2) series there is a typical group of spots differing them from oligopeptide maps of NP-proteins of viruses of other serotypes, particularly of the preceeding serotype H2N2 and the viruses related by hemagglutinin: A/duck/Ukraine/63 (Hav7Neq2) and A/horse/Miami/63 (Heq2Neq2). NP-proteins of the old A/swine/Iowa/30 and new A/New Jersey/76 strains of swine influenza viruses belonging to the same serotype Hsw1N1 differ from each other but are similar to NP-proteins of viruses of H0N1 and H1N1 serotypes, respectively.
通过肽图分析对甲型流感病毒核蛋白(NP蛋白)的蛋白质进行的比较研究表明,其在一个漂移系列内的变异性较小,而在属于不同血清型的毒株中则相当显著。在香港(H3N2)系列病毒NP蛋白的寡肽图中,有一组典型的斑点,使其与其他血清型病毒NP蛋白的寡肽图不同,特别是与之前的血清型H2N2病毒以及通过血凝素相关的病毒:A/鸭/乌克兰/63(Hav7Neq2)和A/马/迈阿密/63(Heq2Neq2)不同。属于同一血清型Hsw1N1的旧型A/猪/爱荷华/30和新型A/新泽西/76猪流感病毒株的NP蛋白彼此不同,但分别与H0N1和H1N1血清型病毒的NP蛋白相似。