散发性急性病毒性肝炎中的肝炎相关抗原
Hepatitis-associated antigen in sporadic cases of acute viral hepatitis.
作者信息
Kelen A E, Hathaway A E, McLeod D A, Nagler F P
出版信息
Can Med Assoc J. 1972 Jan 8;106(1):32-5.
Serum specimens collected during the period from September 1970 to April 1971 from hospitalized patients and apparently healthy staff members at risk were tested for the presence of hepatitis-associated antigen (HAA) by the parallel use of three techniques: the complement fixation test, crossover-electrophoresis and immuno-electronmicroscopy.Out of a total of 204 persons investigated 63 (30.9%) were found to harbour the antigen. The HAA-positive sera originated almost exclusively from sporadic cases of acute viral hepatitis (clinically diagnosed as "infectious hepatitis" or "serum hepatitis"). The great majority of the hepatitis cases studied had a history of drug addiction.
1970年9月至1971年4月期间，从住院患者以及有感染风险的看似健康的工作人员身上采集血清样本，通过同时使用三种技术检测是否存在肝炎相关抗原（HAA）：补体结合试验、交叉电泳和免疫电子显微镜。在总共调查的204人中，发现63人（30.9%）携带该抗原。HAA阳性血清几乎完全来自急性病毒性肝炎的散发病例（临床诊断为“传染性肝炎”或“血清性肝炎”）。所研究的大多数肝炎病例都有药物成瘾史。
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