Sutton R N, Marston S D, Emond R T
J Clin Pathol. 1971 Dec;24(9):801-4. doi: 10.1136/jcp.24.9.801.
Complement-fixing antibodies against an antigen prepared from the EB3 line of cultured Burkitt tumour cells were studied in various groups of patients and control individuals. Higher antibody titres were observed in patients with Burkitt's tumour than in African patients with other diagnoses. Significantly more medical students and nurses with a history of infectious mononucleosis possessed antibodies than those with no such history. Low levels of antibody were observed in patients during the acute phase of infectious mononucleosis and these levels were significantly lower than those in patients admitted to the same hospital with other diagnoses. During the early months following the acute phase of illness, EB complement-fixing antibodies remained stationary or apparently declined in titre but, in patients tested one or more years later, significantly higher antibody levels were observed.
对从培养的伯基特氏瘤细胞EB3系制备的抗原的补体结合抗体，在不同组的患者和对照个体中进行了研究。观察到伯基特氏瘤患者的抗体滴度高于其他诊断的非洲患者。有传染性单核细胞增多症病史的医学生和护士拥有抗体的人数明显多于无此病史者。传染性单核细胞增多症急性期患者的抗体水平较低，且这些水平显著低于因其他诊断入住同一医院的患者。在疾病急性期后的最初几个月里，EB补体结合抗体滴度保持稳定或明显下降，但在一年或多年后接受检测的患者中，观察到抗体水平显著升高。
