3',5'-环磷酸腺苷在大肠杆菌色氨酸酶产生过程中的作用位点。
Site of action of 3',5'-cyclic adenosine monophosphate in production of tryptophanase in Escherichia coli.
作者信息
Immken L, Apirion D
出版信息
Genetics. 1972 Jan;70(1):175-80. doi: 10.1093/genetics/70.1.175.
Abstract
3',5' cyclic-AMP (cAMP) will stimulate the rate of tryptophanase synthesis in Escherichia coli cultures induced with tryptophan. Adding cAMP after the initiation of messenger RNA synthesis was blocked by rifampicin, did not stimulate tryptophanase synthesis. This indicates that cAMP acts at initiation of either transcription or translation and not at the level of chain elongation of either the messenger or the polypeptide chain.
摘要
3',5' 环磷酸腺苷（cAMP）会刺激用色氨酸诱导的大肠杆菌培养物中色氨酸酶的合成速率。在用利福平阻断信使核糖核酸（mRNA）合成起始后添加cAMP，并不会刺激色氨酸酶的合成。这表明cAMP作用于转录或翻译的起始阶段，而不是在信使或多肽链的链延伸水平。
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本文引用的文献
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