环磷酸鸟苷对大肠杆菌完整细胞中受分解代谢物阻遏敏感的酶合成的影响。
Effect of cyclic guanosine 3,5-monophosphate on the synthesis of enzymes sensitive to caatabolite repression in intact cells of Escherichia coli.
作者信息
Artman M, Werthamer S
出版信息
J Bacteriol. 1974 Nov;120(2):980-3. doi: 10.1128/jb.120.2.980-983.1974.
Abstract
Cyclic guanosine 3',5'-monophosphate inhibits the synthesis of beta-galactosidase and tryptophanase in cultures of Escherichia coli growing in minimal media with glucose or glycerol as the carbon source. Cyclic guanosine 3',5'-monophosphate acts at the transcriptional level in the lac operon, it exerts its action at the promoter site of the operon, and requires the presence of functional cyclic adenosine 3',5'-monophosphate receptor protein.
摘要
环鸟苷 3',5'-单磷酸抑制以葡萄糖或甘油作为碳源在基本培养基中生长的大肠杆菌培养物中β-半乳糖苷酶和色氨酸酶的合成。环鸟苷 3',5'-单磷酸在乳糖操纵子的转录水平起作用，它在操纵子的启动子位点发挥作用，并且需要功能性环腺苷 3',5'-单磷酸受体蛋白的存在。
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