Vendsborg P B
Acta Psychiatr Scand. 1979 Mar;59(3):306-16. doi: 10.1111/j.1600-0447.1979.tb06969.x.
Intravenous glucose tolerance was measured in manic-melancholic patients given one daily lithium-dose for relapse prevention. It was found that glucose tolerance was increased for some hours after each lithium administration. In the first week of treatment glucose disposal rate was increased up to 12 h after lithium ingestion. In long-term treated patients glucose tolerance was increased 2 h after administration but not 12 h after. Fasting glucose was increased 2 h after lithium administration in long-term treated patients. Concomitant changes in lactate triglycerides, free-glycerol and electrolytes were measured in serum.
对接受每日一次锂剂预防复发治疗的躁狂-抑郁患者进行静脉葡萄糖耐量测试。结果发现，每次服用锂剂后的数小时内葡萄糖耐量会增加。在治疗的第一周，锂剂摄入后长达12小时的葡萄糖处置率增加。长期接受治疗的患者在给药后2小时葡萄糖耐量增加，但12小时后未增加。长期接受治疗的患者在锂剂给药后2小时空腹血糖升高。同时测量血清中乳酸、甘油三酯、游离甘油和电解质的变化。
