关于致癌物N-2-芴基乙酰胺的肝癌致癌性与其在大鼠体内的代谢活化之间的相关性 - Suppr | 超能文献

On the correlation between the hepatocarcinogenicity of the carcinogen, N-2-fluorenylacetamide, and its metabolic activation by the rat.

作者信息

Gutmann H R, Malejka-Giganti D, Barry E J, Rydell R E

出版信息

Cancer Res. 1972 Jul;32(7):1554-61.

Abstract

摘要

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On the correlation between the hepatocarcinogenicity of the carcinogen, N-2-fluorenylacetamide, and its metabolic activation by the rat.关于致癌物N-2-芴基乙酰胺的肝癌致癌性与其在大鼠体内的代谢活化之间的相关性

Cancer Res. 1972 Jul;32(7):1554-61.

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The carcinogenicity of the o-methoxy derivatives of N-2-fluorenylacetamide and of related compounds in the rat.N-2-芴基乙酰胺的邻甲氧基衍生物及相关化合物对大鼠的致癌性。

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Cancer Res. 1967 Aug;27(8):1443-55.

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The carcinogenicity of fluorenylhydroxamic acids and N-acetoxy-N-fluorenylacetamides for the rat as related to the reactivity of the esters toward nucleophiles.芴基异羟肟酸和N-乙酰氧基-N-芴基乙酰胺对大鼠的致癌性与酯对亲核试剂的反应活性的关系。

Cancer Res. 1975 Feb;35(2):447-59.

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Relationship of metabolic activation of N-hydroxy-N-acylarylamines to biological response in the liver and mammary gland of the female CD rat.雌性CD大鼠肝脏和乳腺中N-羟基-N-酰基芳胺的代谢活化与生物学反应的关系

Cancer Res. 1981 Nov;41(11 Pt 1):4346-53.

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Sex differences in cell proliferation and N-hydroxy-2-acetylaminofluorene sulfotransferase levels in rat liver during 2-acetylaminofluorene administration.在给予2-乙酰氨基芴期间大鼠肝脏中细胞增殖和N-羟基-2-乙酰氨基芴磺基转移酶水平的性别差异。

Cancer Res. 1972 Jul;32(7):1590-4.

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Depression of enzymic esterification of N-hydroxy-AAF in the liver during aminoazo dye carcinogenesis in the rat.大鼠氨基偶氮染料致癌过程中肝脏中N-羟基-AAF酶促酯化作用的抑制。

Res Commun Chem Pathol Pharmacol. 1973 Mar;5(2):421-9.

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Cocarcinogenesis: the interaction of chemical and physical agents.

Radiat Res. 1971 Sep;47(3):644-59.

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Further evidence for two types of adducts of N-hydroxy-2-fluorenylacetamide with rat-liver proteins.N-羟基-2-芴基乙酰胺与大鼠肝脏蛋白两种加合物的进一步证据。

Chem Biol Interact. 1970 Aug;2(2):158-9. doi: 10.1016/0009-2797(70)90048-7.

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Increased activity of polynucleotide ligase from rat hepatoma induced by N-2-fluorenylacetamide.N-2-芴基乙酰胺诱导的大鼠肝癌中多核苷酸连接酶活性增加。

Cancer Res. 1972 May;32(5):886-8.

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