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On the correlation between the hepatocarcinogenicity of the carcinogen, N-2-fluorenylacetamide, and its metabolic activation by the rat.

作者信息

Gutmann H R, Malejka-Giganti D, Barry E J, Rydell R E

出版信息

Cancer Res. 1972 Jul;32(7):1554-61.

PMID:4337834
Abstract
摘要

相似文献

1
On the correlation between the hepatocarcinogenicity of the carcinogen, N-2-fluorenylacetamide, and its metabolic activation by the rat.关于致癌物N-2-芴基乙酰胺的肝癌致癌性与其在大鼠体内的代谢活化之间的相关性
Cancer Res. 1972 Jul;32(7):1554-61.
2
The carcinogenicity of the o-methoxy derivatives of N-2-fluorenylacetamide and of related compounds in the rat.N-2-芴基乙酰胺的邻甲氧基衍生物及相关化合物对大鼠的致癌性。
Cancer Res. 1968 Feb;28(2):234-44.
3
The conversion of noncarcinogenic aromatic amides to carcinogenic arylhydroxamic acids by synthetic N-hydroxylation.通过合成N-羟基化将非致癌性芳香酰胺转化为致癌性芳基异羟肟酸。
Cancer Res. 1967 Aug;27(8):1443-55.
4
The carcinogenicity of fluorenylhydroxamic acids and N-acetoxy-N-fluorenylacetamides for the rat as related to the reactivity of the esters toward nucleophiles.芴基异羟肟酸和N-乙酰氧基-N-芴基乙酰胺对大鼠的致癌性与酯对亲核试剂的反应活性的关系。
Cancer Res. 1975 Feb;35(2):447-59.
5
Relationship of metabolic activation of N-hydroxy-N-acylarylamines to biological response in the liver and mammary gland of the female CD rat.雌性CD大鼠肝脏和乳腺中N-羟基-N-酰基芳胺的代谢活化与生物学反应的关系
Cancer Res. 1981 Nov;41(11 Pt 1):4346-53.
6
Sex differences in cell proliferation and N-hydroxy-2-acetylaminofluorene sulfotransferase levels in rat liver during 2-acetylaminofluorene administration.在给予2-乙酰氨基芴期间大鼠肝脏中细胞增殖和N-羟基-2-乙酰氨基芴磺基转移酶水平的性别差异。
Cancer Res. 1972 Jul;32(7):1590-4.
7
Depression of enzymic esterification of N-hydroxy-AAF in the liver during aminoazo dye carcinogenesis in the rat.大鼠氨基偶氮染料致癌过程中肝脏中N-羟基-AAF酶促酯化作用的抑制。
Res Commun Chem Pathol Pharmacol. 1973 Mar;5(2):421-9.
8
Cocarcinogenesis: the interaction of chemical and physical agents.
Radiat Res. 1971 Sep;47(3):644-59.
9
Further evidence for two types of adducts of N-hydroxy-2-fluorenylacetamide with rat-liver proteins.N-羟基-2-芴基乙酰胺与大鼠肝脏蛋白两种加合物的进一步证据。
Chem Biol Interact. 1970 Aug;2(2):158-9. doi: 10.1016/0009-2797(70)90048-7.
10
Increased activity of polynucleotide ligase from rat hepatoma induced by N-2-fluorenylacetamide.N-2-芴基乙酰胺诱导的大鼠肝癌中多核苷酸连接酶活性增加。
Cancer Res. 1972 May;32(5):886-8.

引用本文的文献

1
Pathobiologic and metabolic aspects of mammary gland tumorigenesis by N-substituted aryl compounds.N-取代芳基化合物诱发乳腺肿瘤发生的病理生物学和代谢方面
Environ Health Perspect. 1983 Mar;49:175-83. doi: 10.1289/ehp.8349175.
2
Sex differences in the biotransformation of 2-acetylaminofluorene in cultured rat hepatocytes.培养的大鼠肝细胞中2-乙酰氨基芴生物转化的性别差异。
Cell Biol Toxicol. 1986 Jun;2(2):271-81. doi: 10.1007/BF00122695.
3
Metabolic activation of diethylstilbestrol and aminostilbene-derivatives.
Arch Toxicol. 1977 Dec 30;39(1-2):21-30. doi: 10.1007/BF00343272.