Metabolic activation of diethylstilbestrol and aminostilbene-derivatives.
作者信息
Neumann H G, Metzler M, Töpner W
出版信息
Arch Toxicol. 1977 Dec 30;39(1-2):21-30. doi: 10.1007/BF00343272.
PMID:579979
Abstract
Diethylstilbestrol and trans-4-dimethylaminostilbene are metabolically activated and several of their metabolites are able to react with cellular macromolecules. Some of the problems are discussed which are encountered in linking a particular metabolite with the mutagenic and carcinogenic properties of these compounds.
摘要
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