Barac-Nieto M, Spurr G B, Lotero H, Maksud M G, Dahners H W
Am J Clin Nutr. 1979 May;32(5):981-91. doi: 10.1093/ajcn/32.5.981.
Body composition was studied in severely undernourished adult male inhabitants of a rural area of Colombia to evaluate the extent and the time course of the changes occurring upon nutritional repletion. During a 45-day basal period on a low (26g/day) protein diet containing adequate calories, body fat depots increased significantly (mean +/- SD = +3.02 +/- 2.9 kg), and there was a significant decrease in cell hydration from 81.8 to 76.4% (-5.4 +/- 9.1%). Upon protein repletion (100 g/day), cell hydration decreased significantly to 71.4%, while body cell mass increased markedly (9.0 +/- 1.1 kg). During protein repletion, muscle cell mass increased significantly (+5.5 +/- 0.6 kg) and rapidly, while the increase in nonmuscle cells (+3.5 +/- 3.8 kg) and specifically in red cell mass lagged behind. With repletion, the changes in the absolute values for plasma volume (+0.4 +/- 0.13 liters) were significant, but those in extracellular fluid volume (-0.7 +/- 1.9 liters) were not. Thus, the major compositional changes observed occurred in the body fat and the body cell mass components; these occurred independently of each other.
对哥伦比亚某农村地区严重营养不良的成年男性居民的身体成分进行了研究，以评估营养补充后发生变化的程度和时间进程。在为期45天的基础期内，食用含足够热量的低蛋白（26克/天）饮食，身体脂肪储备显著增加（平均值±标准差=+3.02±2.9千克），细胞水合作用从81.8%显著降至76.4%（-5.4±9.1%）。补充蛋白质（100克/天）后，细胞水合作用显著降至71.4%，而身体细胞质量显著增加（9.0±1.1千克）。在蛋白质补充期间，肌肉细胞质量显著增加（+5.5±0.6千克）且增加迅速，而非肌肉细胞（+3.5±3.8千克）尤其是红细胞质量的增加则滞后。随着营养补充，血浆容量绝对值的变化（+0.4±0.13升）显著，但细胞外液容量的变化（-0.7±1.9升）不显著。因此，观察到的主要成分变化发生在身体脂肪和身体细胞质量成分中；这些变化相互独立发生。
