通过允许性细胞提取物激活猿猴病毒40转化的非允许性细胞中的病毒基因组。
Activation of the viral genome in Simian Virus 40-transformed nonpermissive cells by permissive cell extracts.
作者信息
Suarez H G, Sonenshein G E, Estrade S, Bourali M F, Cassingena R, Tournier P
出版信息
Proc Natl Acad Sci U S A. 1972 May;69(5):1290-3. doi: 10.1073/pnas.69.5.1290.
Abstract
Simian virus 40-transformed nonpermissive cells in which neither infectious viral DNA nor virions had previously been detected reproducibly yield low levels of infectious simian virus-40 DNA after treatment with extracts of normal permissive cells. Virions were obtained in one out of 37 experiments. Activation of the viral genome is detected only with normal permissive cell extracts and only in simian virus 40-transformed cell lines that are rescuable by heterokaryon formation or by treatment with chemicals. The activating factor(s) is insensitive to deoxyribonuclease and ribonuclease, but is sensitive to heat at 56 degrees and to proteolytic enzymes.
摘要
在之前从未可重复检测到感染性病毒DNA或病毒粒子的猿猴病毒40转化的非允许细胞中，用正常允许细胞的提取物处理后，可产生低水平的感染性猿猴病毒40 DNA。在37次实验中有1次获得了病毒粒子。病毒基因组的激活仅在正常允许细胞提取物中检测到，且仅在可通过异核体形成或化学处理拯救的猿猴病毒40转化细胞系中检测到。激活因子对脱氧核糖核酸酶和核糖核酸酶不敏感，但对56摄氏度的热和蛋白水解酶敏感。
相似文献
1
Activation of the viral genome in Simian Virus 40-transformed nonpermissive cells by permissive cell extracts.通过允许性细胞提取物激活猿猴病毒40转化的非允许性细胞中的病毒基因组。
Proc Natl Acad Sci U S A. 1972 May;69(5):1290-3. doi: 10.1073/pnas.69.5.1290.
2
Further studies on SV40 permissive cell protein factor(s) allowing rescue of infectious virus and viral DNA from non-shedder SV40-transformed cells.
Int J Cancer. 1974 Mar 15;13(3):311-8. doi: 10.1002/ijc.2910130306.
3
Demonstration of infectious deoxyribonucleic acid in transformed cells. I. Recovery of simian virus 40 from yielder and nonyielder transformed cells.转化细胞中传染性脱氧核糖核酸的证明。I. 从产生病毒和不产生病毒的转化细胞中回收猴病毒40
J Virol. 1972 Sep;10(3):399-409. doi: 10.1128/JVI.10.3.399-409.1972.
4
Response of simian virus 40-transformed cell lines and cell hybrids to superinfection with simian virus 40 and its deoxyribonucleic acid.猿猴病毒40转化细胞系和细胞杂种对猿猴病毒40及其脱氧核糖核酸重叠感染的反应。
J Virol. 1969 Oct;4(4):348-55. doi: 10.1128/JVI.4.4.348-355.1969.
5
Synthesis of SV40 capsid antigen(s) in heterokaryocytes formed by fusion of nonpermissive with permissive cells.
Virology. 1974 Apr;58(2):609-11. doi: 10.1016/0042-6822(74)90097-x.
6
Enhancing effect of green monkey kidney cell extract on the transformation of mouse cells by SV40.绿猴肾细胞提取物对SV40诱导小鼠细胞转化的增强作用。
Int J Cancer. 1974 Jul 15;14(1):26-31. doi: 10.1002/ijc.2910140104.
7
The induction of SV40-transformed chinese hamster and mouse kidney cells by mitomycin C.
Intervirology. 1975;5(5):305-12. doi: 10.1159/000149927.
8
Simian virus 40-chinese hamster kidney cell interaction. II. The semipermissivity of the cell system.猿猴病毒40-中国仓鼠肾细胞相互作用。II. 细胞系统的半允许性。
Arch Virol. 1976;50(1-2):137-46. doi: 10.1007/BF01318008.
9
Assignment of the integration site for simian virus 40 to chromosome 17 in GM54VA, a human cell line transformed by simian virus 40.在经猿猴病毒40转化的人类细胞系GM54VA中，将猿猴病毒40的整合位点定位到17号染色体上。
Proc Natl Acad Sci U S A. 1977 Jan;74(1):315-8. doi: 10.1073/pnas.74.1.315.
10
Enhancement of simian virus 40 infection in simian and human cells by permissive cell extracts.通过允许性细胞提取物增强猿猴病毒40在猿猴和人类细胞中的感染。
Proc Soc Exp Biol Med. 1974 Sep;146(4):1014-20. doi: 10.3181/00379727-146-38238.
引用本文的文献
1
Preparation and properties of an inhibitory extract from frog virus 3 particles.青蛙病毒3颗粒抑制性提取物的制备及其性质
J Virol. 1973 May;11(5):694-701. doi: 10.1128/JVI.11.5.694-701.1973.
本文引用的文献
1
SV40-INDUCED TRANFORMATION OF HUMAN DIPLOID CELLS: CRISIS AND RECOVERY.SV40诱导的人二倍体细胞转化：危机与恢复。
J Cell Comp Physiol. 1965 Feb;65:69-83. doi: 10.1002/jcp.1030650110.
2
INFECTION OF HUMAN AND SIMIAN TISSUE CULTURES WITH ROUS SARCOMA VIRUS.劳斯肉瘤病毒对人和猴组织培养物的感染
Proc Natl Acad Sci U S A. 1964 Jul;52(1):53-9. doi: 10.1073/pnas.52.1.53.
3
BIOLOGIC CHARACTERISTICS OF A CONTINUOUS KIDNEY CELL LINE DERIVED FROM THE AFRICAN GREEN MONKEY.源自非洲绿猴的连续肾细胞系的生物学特性
J Immunol. 1963 Sep;91:416-24.
4
Propagation in a fluid medium of a human epidermoid carcinoma, strain KB.人表皮样癌KB株在流体介质中的增殖
Proc Soc Exp Biol Med. 1955 Jul;89(3):362-4. doi: 10.3181/00379727-89-21811.
5
A membrane effect of basic polymers dependent on molecular size.碱性聚合物的膜效应取决于分子大小。
Nature. 1967 Aug 26;215(5104):934-6. doi: 10.1038/215934a0.
6
Activation of infectious SV40 synthesis in transformed cells.转化细胞中感染性SV40合成的激活。
Proc Natl Acad Sci U S A. 1968 Aug;60(4):1239-46. doi: 10.1073/pnas.60.4.1239.
7
Properties of an SV40-transformed African green monkey kidney (BSC-1) cell line.
Int J Cancer. 1972 Mar 15;9(2):324-33. doi: 10.1002/ijc.2910090210.
8
Tumor-producing viruses.致瘤病毒
Medicina (B Aires). 1969 Nov-Dec;29(6):513-38.
9
Transformation of green monkey kidney cells by SV40 genome: the establishment of transformed cell lines and the replication of human adenoviruses and SV40 in transformed cells.SV40基因组对绿猴肾细胞的转化：转化细胞系的建立以及人腺病毒和SV40在转化细胞中的复制。
Virology. 1971 Jul;45(1):163-71. doi: 10.1016/0042-6822(71)90123-1.
10
Superinfection of simian virus 40-transformed permissive cells with simian virus 40.用猿猴病毒40对猿猴病毒40转化的允许细胞进行双重感染。
J Virol. 1970 Nov;6(5):644-51. doi: 10.1128/JVI.6.5.644-651.1970.
Zotero 插件