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Radical accumulation in liver microsomal membranes during biotransformation of aromatic amines and nitro compounds.

作者信息

Stier A, Beitz I, Sackmann E

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1972;274(2):189-91. doi: 10.1007/BF00501853.

DOI:10.1007/BF00501853
PMID:4340796
Abstract
摘要

相似文献

1
Radical accumulation in liver microsomal membranes during biotransformation of aromatic amines and nitro compounds.
Naunyn Schmiedebergs Arch Pharmacol. 1972;274(2):189-91. doi: 10.1007/BF00501853.
2
Reductive metabolism of aromatic nitro compounds including carcinogens by rabbit liver preparations.兔肝制剂对包括致癌物在内的芳香族硝基化合物的还原代谢。
Cancer Res. 1986 Mar;46(3):1089-93.
3
Redox cycle of stable mixed nitroxides formed from carcinogenic aromatic amines.
Xenobiotica. 1980 Jul-Aug;10(7-8):661-73. doi: 10.3109/00498258009033800.
4
Function and localization of cytochromes P450 involved in the metabolic activation of food-derived heterocyclic amines.参与食物源性杂环胺代谢活化的细胞色素P450的功能与定位
Princess Takamatsu Symp. 1995;23:145-53.
5
Electron spin resonance-spin trapping. Detection of superoxide formation during aerobic microsomal reduction of nitro-compounds.
Biochem Biophys Res Commun. 1978 May 30;82(2):680-4. doi: 10.1016/0006-291x(78)90928-2.
6
Superoxide radical generation from heterocyclic amines.杂环胺产生超氧自由基。
Princess Takamatsu Symp. 1995;23:103-12.
7
The enzymatic reduction of the N-hydroxy derivatives of 2-acetylaminofluorene and related carcinogens by tissue preparations.组织制剂对2-乙酰氨基芴及相关致癌物的N-羟基衍生物的酶促还原作用。
Cancer Res. 1965 Nov;25(10):1743-52.
8
[The activation of carcinogenic aromatic amines in metabolism].[致癌性芳香胺在代谢中的活化作用]
Klin Wochenschr. 1970 Aug 15;48(16):959-66. doi: 10.1007/BF01484398.
9
Spin labels as enzyme substrates. Heterogeneous lipid distribution in liver microsomal membranes.作为酶底物的自旋标记物。肝微粒体膜中脂质分布不均一。
Biochim Biophys Acta. 1973 Jul 6;311(3):400-8. doi: 10.1016/0005-2736(73)90320-9.
10
Microsomal N- and C-oxidations of carcinogenic aromatic amines and amides.致癌性芳香胺和酰胺的微粒体N-氧化和C-氧化
Natl Cancer Inst Monogr. 1981 Dec(58):101-7.

引用本文的文献

1
Comparative studies on the cumene hydroperoxide- and NADPH-supported N-oxidation of 4-chloroaniline by cytochrome P-450.细胞色素P-450对异丙苯过氧化氢和NADPH支持的4-氯苯胺N-氧化作用的比较研究。
Biochem J. 1983 Jun 15;212(3):539-47. doi: 10.1042/bj2120539.
2
Some historical aspects of N-aryl carcinogens and their metabolic activation.N-芳基致癌物及其代谢活化的一些历史方面
Environ Health Perspect. 1983 Mar;49:3-12. doi: 10.1289/ehp.83493.
3
Ultimate electrophilic carcinogens on cellular nucleophilic reactants. A contribution to the discussion on threshold doses of environmental chemicals.

本文引用的文献

1
Physics and chemistry of spin labels.自旋标记物的物理与化学
Q Rev Biophys. 1970 Feb;3(1):91-136. doi: 10.1017/s003358350000442x.
2
The metabolic activation of carcinogenic aromatic amines and amides.致癌性芳香胺和酰胺的代谢活化
Prog Exp Tumor Res. 1969;11:273-301. doi: 10.1159/000391399.
3
On the metabolic activation of N-hydroxy-N-2-acetylamino-fluorene. II. Simultaneous formation of 2-nitrosofluorene and N-acetoxy-N-2-acetylaminofluorene from N-hydroxy-N-2-acetylaminofluorene via a free radical intermediate.
作用于细胞亲核反应物的终极亲电致癌物。对环境化学品阈剂量讨论的一份贡献。
Arch Toxicol. 1974 Mar 29;32(1):27-38. doi: 10.1007/BF00334609.
4
Desferrioxamine (Desferal) and superoxide free radicals. Formation of an enzyme-damaging nitroxide.去铁胺（去铁敏）与超氧自由基。一种酶损伤性氮氧化物的形成。
Biochem J. 1987 Sep 15;246(3):725-9. doi: 10.1042/bj2460725.
5
Free radicals produced in a nitrosofluorene-unsaturated lipid reaction.
Experientia. 1977 Feb 15;33(2):197-8. doi: 10.1007/BF02124063.
6
A comparative study on the irreversible binding of labeled halothane trichlorofluoromethane, chloroform, and carbon tetrachloride to hepatic protein and lipids in vitro and in vivo.标记的氟烷、三氯氟甲烷、氯仿和四氯化碳在体外和体内与肝脏蛋白质和脂质不可逆结合的比较研究。
Arch Toxicol. 1975 Dec 18;34(4):289-308. doi: 10.1007/BF00353849.
论N-羟基-N-2-乙酰氨基芴的代谢活化。II. 经由自由基中间体从N-羟基-N-2-乙酰氨基芴同时生成2-亚硝基芴和N-乙酰氧基-N-2-乙酰氨基芴
Biochim Biophys Acta. 1971 Jun 22;237(3):556-66. doi: 10.1016/0304-4165(71)90276-5.
4
Radical production in amine oxidation by liver microsomes.肝脏微粒体介导的胺氧化过程中的自由基生成。
Xenobiotica. 1971 Jul-Oct;1(4):499-500. doi: 10.3109/00498257109041516.