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1
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Environ Health Perspect. 1983 Mar;49:3-12. doi: 10.1289/ehp.83493.
2
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Carcinogenicity of aromatic amines and azo dyes and their role in the development of human cancer.芳香胺和偶氮染料的致癌性及其在人类癌症发生中的作用。
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Natl Cancer Inst Monogr. 1981 Dec(58):95-9.
9
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10
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引用本文的文献

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3
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4
Formation and persistence of arylamine DNA adducts in vivo.体内芳胺DNA加合物的形成与持久性。
Environ Health Perspect. 1985 Oct;62:19-30. doi: 10.1289/ehp.856219.
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本文引用的文献

1
The reaction of mustard gas with nucleic acids in vitro and in vivo.芥子气在体外和体内与核酸的反应。
Biochem J. 1960 Dec;77(3):478-84. doi: 10.1042/bj0770478.
2
In vivo combinations between carcinogens and tissue constituents and their possible role in carcinogenesis.致癌物与组织成分在体内的组合及其在致癌过程中的可能作用。
Cancer Res. 1952 Aug;12(8):547-56.
3
Liver tumor inhibition and adrenal histologic responses in rats to which 3'-methyl-4-dimethylaminoazobenzene and 20-methylcholanthrene were simultaneously administered.同时给予3'-甲基-4-二甲基氨基偶氮苯和20-甲基胆蒽的大鼠的肝肿瘤抑制及肾上腺组织学反应
Cancer Res. 1952 May;12(5):356-61.
4
Studies on ethionine. III. Incorporation of ethionine into rat proteins.乙硫氨酸研究。III. 乙硫氨酸掺入大鼠蛋白质的情况。
J Biol Chem. 1951 Oct;192(2):835-50.
5
Electrophoretic studies on the soluble proteins from livers of rats fed aminoazo dyes.对喂食氨基偶氮染料的大鼠肝脏可溶性蛋白质的电泳研究。
Cancer Res. 1951 May;11(5):383-7.
6
Electrophoretic and ultracentrifugal studies on the soluble proteins of various tumors and of livers from rats fed 4-dimethylaminoazobenzene.对喂食4-二甲基氨基偶氮苯的大鼠的各种肿瘤及肝脏的可溶性蛋白质进行的电泳和超速离心研究。
Cancer Res. 1951 May;11(5):376-82.
7
Studies on the formation of protein-bound derivatives of 3,4-benzpyrene in the epidermal fraction of mouse skin.小鼠皮肤表皮部分中3,4-苯并芘蛋白质结合衍生物形成的研究。
Cancer Res. 1951 Feb;11(2):100-8.
8
The carcinogenic action of benzidine.联苯胺的致癌作用。
Cancer. 1950 Sep;3(5):789-804. doi: 10.1002/1097-0142(1950)3:5<789::aid-cncr2820030505>3.0.co;2-u.
9
The apparent binding of radioactive 2-acetylaminofluorene to rat-liver ribonucleic acid in vivo.
Biochim Biophys Acta. 1962 Mar 5;55:403-5. doi: 10.1016/0006-3002(62)90802-8.
10
ON THE STRUCTURE OF THE GLUCURONIDE OF N-HYDROXY-2-ACETYLAMINOFLUORENE.
J Biol Chem. 1965 Mar;240:1011-3.

N-芳基致癌物及其代谢活化的一些历史方面

Some historical aspects of N-aryl carcinogens and their metabolic activation.

作者信息

Miller J A, Miller E C

出版信息

Environ Health Perspect. 1983 Mar;49:3-12. doi: 10.1289/ehp.83493.

DOI:10.1289/ehp.83493
PMID:6339227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1569122/
Abstract

This limited review of the early studies on the activation of the N-aryl carcinogens was written to provide a background for the current research to be presented at this conference on carcinogenesis by N-aryl compounds. Since the work of the past 10 years is too recent to be judged in a historical sense and because those data are much better known by current investigators, this review is generally limited to data up to 1972.

摘要

这篇对N-芳基致癌物激活早期研究的有限综述旨在为本次关于N-芳基化合物致癌作用的会议上即将展示的当前研究提供背景。由于过去十年的研究成果在历史角度上还太新,难以评判,并且当前研究人员对这些数据更为熟知,因此本综述一般限于1972年以前的数据。