• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Factors affecting the activity of the lactate dehydrognease of Streptococcus cremoris.影响嗜热链球菌乳酸脱氢酶活性的因素。
J Bacteriol. 1972 Aug;111(2):397-403. doi: 10.1128/jb.111.2.397-403.1972.
2
Purification and properties of nicotinamide adenine dinucleotide-dependent D- and L- lactate dehydrogenases in a group N streptococcus.N群链球菌中烟酰胺腺嘌呤二核苷酸依赖性D-和L-乳酸脱氢酶的纯化及性质
J Bacteriol. 1972 Aug;111(2):392-6. doi: 10.1128/jb.111.2.392-396.1972.
3
Fructose-1,6-diphosphate-dependent lactate dehydrogenase from a cariogenic streptococcus: purification and regulatory properties.致龋性链球菌中依赖果糖-1,6-二磷酸的乳酸脱氢酶：纯化及调节特性
J Bacteriol. 1972 May;110(2):604-15. doi: 10.1128/jb.110.2.604-615.1972.
4
Properties of a fructose-1,6-diphosphate-activated lactate dehydrogenase from Acholeplasma laidlawii type A.来自A 型莱氏无胆甾原体的果糖-1,6-二磷酸激活的乳酸脱氢酶的特性
J Bacteriol. 1973 Jun;114(3):1025-33. doi: 10.1128/jb.114.3.1025-1033.1973.
5
Fructose 1,6-diphosphate-activated L-lactate dehydrogenase from Streptococcus lactis: kinetic properties and factors affecting activation.来自乳酸链球菌的果糖1,6 - 二磷酸激活的L - 乳酸脱氢酶：动力学特性及影响激活的因素
J Bacteriol. 1977 Jul;131(1):82-91. doi: 10.1128/jb.131.1.82-91.1977.
6
Purificationa and properties of a fructose-1,6-diphosphate-activated lactate dehydrogenase from Streptococcus faecalis.粪链球菌中果糖-1,6-二磷酸激活的乳酸脱氢酶的纯化及性质
J Bacteriol. 1970 Mar;101(3):717-24. doi: 10.1128/jb.101.3.717-724.1970.
7
Production of racemic lactic acid in Pediococcus cerevisiae cultures by two lactate dehydrogenases.两种乳酸脱氢酶在啤酒片球菌培养物中产生消旋乳酸。
J Bacteriol. 1975 Feb;121(2):600-7. doi: 10.1128/jb.121.2.600-607.1975.
8
Purification and properties of a fructose-1,6-diphosphate activated L-lactate dehydrogenase from Staphylococcus epidermidis.表皮葡萄球菌中一种果糖-1,6-二磷酸激活的L-乳酸脱氢酶的纯化及性质
Arch Microbiol. 1975 Nov 7;105(3):303-12. doi: 10.1007/BF00447150.
9
L-Lactate dehydrogenase, FDP-activated, from Streptococcus cremoris.来自乳酸乳球菌的FDP激活型L-乳酸脱氢酶。
Methods Enzymol. 1982;89 Pt D:362-7. doi: 10.1016/s0076-6879(82)89065-4.
10
Purification, characterization, and regulation of a nicotinamide adenine dinucleotide-dependent lactate dehydrogenase from Actinomyces viscosus.来自黏性放线菌的烟酰胺腺嘌呤二核苷酸依赖性乳酸脱氢酶的纯化、特性鉴定及调控
J Bacteriol. 1975 Jun;122(3):1126-35. doi: 10.1128/jb.122.3.1126-1135.1975.

引用本文的文献

1
L-Lactate dehydrogenase from Cyanidioschyzon merolae shows high catalytic efficiency for pyruvate reduction and is inhibited by ATP.来源于嗜热网柄菌的 L-乳酸脱氢酶对于丙酮酸的还原具有很高的催化效率，并且受到 ATP 的抑制。
Plant Mol Biol. 2024 Sep 10;114(5):98. doi: 10.1007/s11103-024-01495-0.
2
NAD-dependent lactate dehydrogenase catalyses the first step in respiratory utilization of lactate by Lactococcus lactis.NAD 依赖性乳酸脱氢酶催化乳球菌呼吸利用乳酸的第一步。
FEBS Open Bio. 2013 Aug 19;3:379-86. doi: 10.1016/j.fob.2013.08.005. eCollection 2013.
3
Regulation of lactose fermentation in group N streptococci.N 群链球菌中乳糖发酵的调控。
Appl Environ Microbiol. 1976 Oct;32(4):474-8. doi: 10.1128/aem.32.4.474-478.1976.
4
The pool of ADP and ATP regulates anaerobic product formation in resting cells of Lactococcus lactis.ADP和ATP的总量调节乳酸乳球菌静止细胞中厌氧产物的形成。
Appl Environ Microbiol. 2004 Sep;70(9):5477-84. doi: 10.1128/AEM.70.9.5477-5484.2004.
5
Reappraisal of the regulation of lactococcal L-lactate dehydrogenase.乳酸乳球菌L-乳酸脱氢酶调控的重新评估
Appl Environ Microbiol. 2004 Mar;70(3):1843-6. doi: 10.1128/AEM.70.3.1843-1846.2004.
6
Relationship between intracellular phosphate, proton motive force, and rate of nongrowth energy dissipation (energy spilling) in Streptococcus bovis JB1.牛链球菌JB1中细胞内磷酸盐、质子动力和非生长能量耗散率（能量溢流）之间的关系
Appl Environ Microbiol. 1998 Mar;64(3):976-81. doi: 10.1128/AEM.64.3.976-981.1998.
7
Isolation and properties of Lactococcus lactis subsp. lactis biovar diacetylactis CNRZ 483 mutants producing diacetyl and acetoin from glucose.乳酸乳球菌乳酸亚种双乙酰变种CNRZ 483从葡萄糖产生双乙酰和乙偶姻的突变体的分离及特性
Appl Environ Microbiol. 1997 Jun;63(6):2293-9. doi: 10.1128/aem.63.6.2293-2299.1997.
8
Bacterial lactate dehydrogenases.细菌乳酸脱氢酶
Microbiol Rev. 1980 Mar;44(1):106-39. doi: 10.1128/mr.44.1.106-139.1980.
9
D-tagatose 1,6-diphosphate aldolase from lactic streptococci: purification, properties, and use in measuring intracellular tagatose 1,6-diphosphate.来自乳酸链球菌的D-塔格糖1,6-二磷酸醛缩酶：纯化、性质及在测定细胞内D-塔格糖1,6-二磷酸中的应用
J Bacteriol. 1982 Aug;151(2):600-8. doi: 10.1128/jb.151.2.600-608.1982.
10
Kinetic parameters of lactate dehydrogenases of some rumen bacterial species, the anaerobic ciliate Isotricha prostoma and mixed rumen microorganisms.一些瘤胃细菌、厌氧纤毛虫原口等毛虫以及混合瘤胃微生物的乳酸脱氢酶动力学参数。
Antonie Van Leeuwenhoek. 1980;46(4):363-81. doi: 10.1007/BF00421983.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
FRUCTOSE-1,6-DIPHOSPHATE REQUIREMENT OF STREPTOCOCCAL LACTIC DEHYDROGENASES.链球菌乳酸脱氢酶对1,6-二磷酸果糖的需求
Science. 1964 Nov 6;146(3645):775-7. doi: 10.1126/science.146.3645.775.
3
THE PREVALENCE AND SIGNIFICANCE OF THE PRODUCT INHIBITION OF ENZYMES.酶的产物抑制作用的发生率及意义
Adv Enzymol Relat Subj Biochem. 1963;25:167-274. doi: 10.1002/9780470122709.ch4.
4
Purification and properties of nicotinamide adenine dinucleotide-dependent D- and L- lactate dehydrogenases in a group N streptococcus.N群链球菌中烟酰胺腺嘌呤二核苷酸依赖性D-和L-乳酸脱氢酶的纯化及性质
J Bacteriol. 1972 Aug;111(2):392-6. doi: 10.1128/jb.111.2.392-396.1972.
5
Physicochemical studies on the lactate dehydrogenase of Streptococcus cremoris US3: the effects of modifiers.嗜热链球菌US3乳酸脱氢酶的物理化学研究：修饰剂的影响
Biochim Biophys Acta. 1971 Nov 13;250(2):271-85. doi: 10.1016/0005-2744(71)90184-7.
6
Purificationa and properties of a fructose-1,6-diphosphate-activated lactate dehydrogenase from Streptococcus faecalis.粪链球菌中果糖-1,6-二磷酸激活的乳酸脱氢酶的纯化及性质
J Bacteriol. 1970 Mar;101(3):717-24. doi: 10.1128/jb.101.3.717-724.1970.

影响嗜热链球菌乳酸脱氢酶活性的因素。

Factors affecting the activity of the lactate dehydrognease of Streptococcus cremoris.

作者信息

Jonas H A, Anders R F, Jago G R

出版信息

J Bacteriol. 1972 Aug;111(2):397-403. doi: 10.1128/jb.111.2.397-403.1972.

DOI:10.1128/jb.111.2.397-403.1972
PMID:4340864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC251296/
Abstract

Studies with partially purified extracts of the nicotinamide adenine dinucleotide-linked l(+)-lactate dehydrogenase of Streptococcus cremoris US3 showed that fructose-1,6-diphosphate (FDP) was essential for the catalytic reduction of pyruvate in the pH range 5.0 to 7.0, outside of which the organism does not grow. In the absence of FDP, enzyme activity was observed only in the region of pH 8.0. The optimal pH for the oxidation of lactate was approximately 8.0 in the presence and absence of FDP. The FDP-activated enzyme was markedly inhibited by inorganic phosphate. The enzyme lost activity on standing at 5 C in alkaline triethanolamine, was quite stable at pH 6.0 to 6.5, and underwent irreversible denaturation below pH 5.0. Inorganic phosphate or FDP increased the stability of the enzyme in alkaline buffers. Some distinguishing properties of individual lactate dehydrogenases, activated by FDP, are discussed.

摘要

对嗜热链球菌US3中烟酰胺腺嘌呤二核苷酸连接的l(+)-乳酸脱氢酶部分纯化提取物的研究表明，在pH值5.0至7.0范围内，果糖-1,6-二磷酸（FDP）对于丙酮酸的催化还原至关重要，在此范围之外该生物体无法生长。在没有FDP的情况下，仅在pH 8.0区域观察到酶活性。无论有无FDP，乳酸氧化的最佳pH值约为8.0。FDP激活的酶受到无机磷酸盐的显著抑制。该酶在碱性三乙醇胺中于5℃放置时会失去活性，在pH 6.0至6.5时相当稳定，在pH 5.0以下会发生不可逆变性。无机磷酸盐或FDP可提高该酶在碱性缓冲液中的稳定性。讨论了由FDP激活的各个乳酸脱氢酶的一些独特性质。