乳酸乳球菌L-乳酸脱氢酶调控的重新评估
Reappraisal of the regulation of lactococcal L-lactate dehydrogenase.
作者信息
van Niel Ed W J, Palmfeldt Johan, Martin Rani, Paese Marco, Hahn-Hägerdal Bärbel
机构信息
Department of Applied Microbiology, Lund University, Lund SE-221 00, Sweden.
出版信息
Appl Environ Microbiol. 2004 Mar;70(3):1843-6. doi: 10.1128/AEM.70.3.1843-1846.2004.
Abstract
Lactococcal lactate dehydrogenases (LDHs) are coregulated at the substrate level by at least two mechanisms: the fructose-1,6-biphosphate/phosphate ratio and the NADH/NAD ratio. Among the Lactococcus lactis species, there are strains that are predominantly regulated by the first mechanism (e.g., strain 65.1) or by the second mechanism (e.g., strain NCDO 2118). A more complete model of the kinetics of the regulation of lactococcal LDH is discussed.
摘要
乳酸乳球菌乳酸脱氢酶（LDHs）在底物水平上至少通过两种机制进行协同调节：果糖-1,6-二磷酸/磷酸比率和NADH/NAD比率。在乳酸乳球菌物种中，有些菌株主要受第一种机制调节（例如65.1菌株），或受第二种机制调节（例如NCDO 2118菌株）。本文讨论了更完整的乳酸乳球菌LDH调节动力学模型。
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