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喷雾对畜栏内空气传播的口蹄疫病毒量的影响。

The effects of spraying on the amounts of airborne foot-and-mouth disease virus present in loose-boxes.

作者信息

Sellers R F, Herniman K A

出版信息

J Hyg (Lond). 1972 Sep;70(3):551-6. doi: 10.1017/s0022172400063130.

DOI:10.1017/s0022172400063130
PMID:4342000
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2130211/
Abstract

The air of loose-boxes which had previously held pigs infected with foot-and-mouth disease was sampled for virus after various procedures. Removal of infected pigs led to a 12- to 16-fold reduction in the amount of virus after 5 min. and a 400-fold reduction after 60 min. After heavy spraying (1.2 mm. of water in 5 min.) the amount of virus was reduced 500-fold compared to 30-fold after light spraying (0.20 mm. of water in 5 min.). The partition of infectivity associated with particle size was measured. The partition found after light spraying was similar to that found 5 min. after the pigs had been removed. Heavy spraying brought about a reduction in the infectivity associated with the large particles (> 6 mum.) but had no effect on particles less than 3 mum. A similar partition was found 60 min. after the pigs had been removed. The findings are discussed in relation to the spread of foot-and-mouth disease by the airborne route.

摘要

在进行各种操作后,对先前饲养过感染口蹄疫猪只的散养栏空气进行病毒采样。清除感染猪只后,5分钟内病毒量减少了12至16倍,60分钟后减少了400倍。重度喷雾(5分钟内喷水1.2毫米)后,病毒量减少了500倍,而轻度喷雾(5分钟内喷水0.20毫米)后减少了30倍。测量了与颗粒大小相关的感染性分布情况。轻度喷雾后发现的分布情况与猪只被移走5分钟后发现的相似。重度喷雾使与大颗粒(>6微米)相关的感染性降低,但对小于3微米的颗粒没有影响。在猪只被移走60分钟后发现了类似的分布情况。结合口蹄疫通过空气传播的途径对这些发现进行了讨论。

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本文引用的文献

1
Multistage liquid impinger.多级液体冲击器。
Bacteriol Rev. 1966 Sep;30(3):559-70. doi: 10.1128/br.30.3.559-570.1966.
2
The epizootiological importance of foot-and-mouth disease carriers. I. Experimentally produced foot-and-mouth disease carriers in susceptible and immune cattle.口蹄疫带毒者的流行病学重要性。I. 易感和免疫牛中实验性产生的口蹄疫带毒者
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Deposition and uptake by cattle of airborn particles.牛对空气中颗粒的沉积与摄取。
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The effects of killing or removal of animals affected with foot-and-mouth disease on the amounts of airborne virus present in looseboxes.
Br Vet J. 1971 Aug;127(8):358-65. doi: 10.1016/s0007-1935(17)37440-7.
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The growth and persistence of foot-and-mouth disease virus in the bovine mammary gland.口蹄疫病毒在牛乳腺中的生长与持续存在
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Lee wave hypothesis for the initial pattern of spread during the 1967-68 foot and mouth epizootic.1967 - 1968年口蹄疫 epizootic 期间传播初始模式的李波假说 。(注:这里epizootic 直译为“兽疫流行”,在兽医领域常用来指动物疾病的流行,整体语境可能是关于口蹄疫流行期间传播模式基于李波假说的研究内容,但epizootic 这个词在中文里没有完全对应的简洁词汇,若有更详细背景信息,可能翻译会更精准。)
Nature. 1970 Aug 22;227(5260):860-2. doi: 10.1038/227860b0.
9
Windborne dispersal of foot and mouth virus.口蹄疫病毒的空气传播
Nature. 1970 Jan 3;225(5227):98-9. doi: 10.1038/225098a0.
10
Airborne excretion of foot-and-mouth disease virus.口蹄疫病毒的空气传播排泄
J Hyg (Lond). 1969 Dec;67(4):671-7. doi: 10.1017/s0022172400042121.