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关于16S核糖体核糖核酸中转录后修饰核苷酸的观察

Observations on the post-transcriptionally modified nucleotides in the 16S ribosomal ribonucleic acid.

作者信息

Sogin M L, Pechman K J, Zablen L, Lewis B J, Woese C R

出版信息

J Bacteriol. 1972 Oct;112(1):13-6. doi: 10.1128/jb.112.1.13-16.1972.

Abstract

The 16S (18S) ribosomal ribonucleic acids from a number of organisms were screened for the presence of (some of) the post-transcriptionally modified oligomers found in Escherichia coli 16S ribosomal ribonucleic acid. All prokaryotic 16S species contained all of the modified oligomers tested, with the sole exception that one such oligomer was missing in Alcaligenes faecalis. The post-transcriptional modifications in all of these oligomers except one appear to occur at the later stagesin ribosomal maturation.

摘要

对多种生物的16S(18S)核糖体核糖核酸进行了筛查,以检测是否存在大肠杆菌16S核糖体核糖核酸中发现的(部分)转录后修饰的寡聚物。所有原核生物的16S种类都含有所有测试的修饰寡聚物,唯一的例外是粪产碱菌中缺少一种这样的寡聚物。除一种寡聚物外,所有这些寡聚物的转录后修饰似乎都发生在核糖体成熟的后期阶段。

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