关节软骨的自身免疫原性。
The auto-immunogenicity of articular cartilage.
作者信息
Langer F, Gross A E, Greaves M F
出版信息
Clin Exp Immunol. 1972 Sep;12(1):31-7.
Abstract
Rats injected with syngeneic chondrocytes or cartilage shavings develop autoreactivity as assayed by the leucocyte migration inhibition test. It is suggested that chondrocyte specific differentiation antigen(s), normally sequestered from the immune system, once exposed experimentally by enzyme treatment or in some human pathological situations are recognized as foreign immunogens and induce a lymphocyte response.
摘要
通过白细胞迁移抑制试验检测发现，注射同基因软骨细胞或软骨屑的大鼠会产生自身反应性。有人提出，软骨细胞特异性分化抗原通常与免疫系统隔绝，一旦通过酶处理或在某些人类病理情况下被实验性地暴露，就会被识别为外来免疫原并诱导淋巴细胞反应。
相似文献
1
The auto-immunogenicity of articular cartilage.关节软骨的自身免疫原性。
Clin Exp Immunol. 1972 Sep;12(1):31-7.
2
Immunogenicity of allograft articular cartilage.
J Bone Joint Surg Am. 1974 Mar;56(2):297-304.
3
Matrix antigens in allografts. II. The cell-mediated response.
Clin Orthop Relat Res. 1983 Jan-Feb(172):277-80.
4
Immature joint cartilage and the homograft reaction.未成熟关节软骨与同种异体移植反应。
Br J Surg. 1971 Apr;58(4):300.
5
6
Immunobiology of cartilage.软骨的免疫生物学
Semin Arthritis Rheum. 1975 Aug;5(1):1-40. doi: 10.1016/0049-0172(75)90021-9.
7
Indirect migration inhibition test in xenogeneic systems. 3. Cellular immunity to kidney grafts.异种系统中的间接迁移抑制试验。3. 对肾移植的细胞免疫。
Arch Immunol Ther Exp (Warsz). 1971;19(3):377-80.
8
[In vivo synthesis of cartilage after transplantation of chondrocytes in animal experiments (author's transl)].动物实验中软骨细胞移植后软骨的体内合成（作者译）
Chir Forum Exp Klin Forsch. 1980:47-51.
9
10
[Review of recent contributions on the physiopathology of articular cartilage. II. Metabolism; mechanical properties; antigenicity].[关节软骨生理病理学近期研究成果综述。II. 代谢；力学性能；抗原性]
Rev Rhum Mal Osteoartic. 1972 Feb;39(2):157-65.
引用本文的文献
1
Antigenic and immunogenic properties of chondrocytes. Implications for chondrocyte therapeutic transplantation and pathogenesis of inflammatory and degenerative joint diseases.软骨细胞的抗原性和免疫原性特性。对软骨细胞治疗性移植以及炎性和退行性关节疾病发病机制的影响。
Cent Eur J Immunol. 2018;43(2):209-219. doi: 10.5114/ceji.2018.77392. Epub 2018 Jun 30.
2
In search of chondrocyte-specific antigen.寻找软骨细胞特异性抗原。
Cent Eur J Immunol. 2018;43(2):132-138. doi: 10.5114/ceji.2018.77382. Epub 2018 Jun 30.
3
Experimental study of tissue-engineered cartilage allograft with RNAi chondrocytes in vivo.体内 RNAi 软骨细胞组织工程化软骨同种异体移植物的实验研究。
Ther Clin Risk Manag. 2014 May 8;10:335-40. doi: 10.2147/TCRM.S51518. eCollection 2014.
4
Fresh osteochondral allografts for posttraumatic knee defects: long-term followup.新鲜同种异体骨软骨移植治疗创伤后膝关节缺损：长期随访
Clin Orthop Relat Res. 2008 Aug;466(8):1863-70. doi: 10.1007/s11999-008-0282-8. Epub 2008 May 9.
5
Humoral immune response against minor collagens type IX and XI in patients with cartilage graft resorption after reconstructive surgery.重建手术后软骨移植吸收患者针对IX型和XI型次要胶原蛋白的体液免疫反应。
Ann Rheum Dis. 1994 Apr;53(4):229-34. doi: 10.1136/ard.53.4.229.
6
Pig articular cartilage in organ culture. Effect of enzymatic depletion of the matrix on response of chondrocytes to complement-sufficient antiserum against pig erythrocytes.器官培养中的猪关节软骨。基质酶解对软骨细胞对猪红细胞补体充足抗血清反应的影响。
Ann Rheum Dis. 1974 Nov;33(6):500-8. doi: 10.1136/ard.33.6.500.
7
Cartilage antigen dependent lymphotoxin release. Immunopathological significance in articular destructive disorders.软骨抗原依赖性淋巴毒素释放。在关节破坏性疾病中的免疫病理学意义。
Ann Rheum Dis. 1974 Sep;33(5):446-52. doi: 10.1136/ard.33.5.446.
8
Antigenic profiles of human, bovine and canine articular chondrocytes.人、牛和犬关节软骨细胞的抗原谱
Cell Tissue Res. 1986;244(2):359-69. doi: 10.1007/BF00219212.
9
The antigenicity of chondrocytes.软骨细胞的抗原性。
Immunology. 1977 Jul;33(1):141-5.
10
The stimulation of lymphocytes by chondrocytes in mixed cultures.混合培养中软骨细胞对淋巴细胞的刺激作用。
Clin Exp Immunol. 1976 Apr;24(1):102-9.
本文引用的文献
1
Absorption of autogenous cartilage grafts in man.
Br J Plast Surg. 1956 Oct;9(3):177-85. doi: 10.1016/s0007-1226(56)80032-5.
2
3
The dual nature of epiphysial cartilage.
J Bone Joint Surg Br. 1967 May;49(2):351-61.
4
Human lymphocyte migration as a parameter of hypersensitivity.人类淋巴细胞迁移作为超敏反应的一个参数。
Acta Med Scand. 1967 Feb;181(2):247-56. doi: 10.1111/j.0954-6820.1967.tb07255.x.
5
Cartilage formation after homotransplantation of isolated chondrocytes.分离软骨细胞同种异体移植后的软骨形成
Transplantation. 1965 Nov;3(6):737-47. doi: 10.1097/00007890-196511000-00005.
6
Isolation and characterization of calcifying matrix vesicles from epiphyseal cartilage.从骨骺软骨中分离和鉴定钙化基质小泡。
Proc Natl Acad Sci U S A. 1970 Nov;67(3):1513-20. doi: 10.1073/pnas.67.3.1513.
7
In vitro assay of cell-mediated immunity: the inhibition of migration of sensitized human lymphocytes by HL-A antigens.细胞介导免疫的体外测定：HL-A抗原对致敏人淋巴细胞迁移的抑制作用。
Clin Exp Immunol. 1970 Apr;6(4):445-55.
8
Homotransplantation of isolated epiphyseal and articular cartilage chondrocytes into joint surfaces of rabbits.将分离的骨骺和关节软骨软骨细胞同种移植到兔关节表面。
Nature. 1971 Apr 9;230(5293):385-8. doi: 10.1038/230385a0.
9
Collagenase and rheumatoid arthritis.
Arthritis Rheum. 1970 Jan-Feb;13(1):83-94. doi: 10.1002/art.1780130109.
10
Homotransplantation of articular cartilage and isolated chondrocytes. An experimental study in rabbits.
J Bone Joint Surg Br. 1968 Feb;50(1):184-97.
Zotero 插件