白血病相关小鼠抗原G IX表达所需的第二个基因的定位。
Location of the second gene required for expression of the leukemia-associated mouse antigens G IX .
作者信息
Stockert E, Sato H, Itakura K, Boyse E A, Old L J, Hutton J J
出版信息
Science. 1972 Nov 24;178(4063):862-3. doi: 10.1126/science.178.4063.862.
PMID:4343697
Abstract
Some mouse strains express G(IX) antigen on their thymocytes; others do not. Expression depends on two genes, Gv-1 and Gv-2, in linkage groups IX and I, respectively. Cells producing leukemia virus, however, express G(IX) antigen regardless of their inherited Gv-1 and Gv-2 genotype.
摘要
一些小鼠品系在其胸腺细胞上表达G(IX)抗原；另一些则不表达。这种表达分别取决于连锁群IX和I中的两个基因Gv-1和Gv-2。然而，产生白血病病毒的细胞，无论其遗传的Gv-1和Gv-2基因型如何，都会表达G(IX)抗原。
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