血清gp70的产生受小鼠7号染色体上一个基因的调控。
Serum gp70 production regulated by a gene on murine chromosome 7.
作者信息
Maruyama N, Lindstrom C O, Sato H, Dixon F J
出版信息
Immunogenetics. 1983;18(4):365-71. doi: 10.1007/BF00372469.
PMID:6629441
Abstract
We mated 129 mice (prototype strain of GIX+) with C57BL/6 mice (prototype strain of GIX-) and thereby identified the gene controlling enhancement of serum gp70 production after lipopolysaccharide (LPS) injection. This gene has been tentatively designated Sgp-2. Sgp-2 is linked with the Hbb locus on chromosome 7. The estimated frequency of recombination between Sgp-2 and Hbb in this setting is about 20%.
摘要
我们将129只小鼠（GIX +原型品系）与C57BL / 6小鼠（GIX -原型品系）进行交配，从而确定了控制脂多糖（LPS）注射后血清gp70产生增强的基因。该基因已被暂时命名为Sgp-2。Sgp-2与7号染色体上的Hbb基因座相连。在这种情况下，Sgp-2与Hbb之间的重组频率估计约为20％。
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