ICI 125,211：一种作用于组胺H2受体的新型胃分泌抑制剂。 - Suppr

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ICI 125,211: a new gastric antisecretory agent acting on histamine H2-receptors.

作者信息

Yellin T O, Buck S H, Gilman D J, Jones D F, Wardleworth J M

出版信息

Life Sci. 1979 Dec 3;25(23):2001-9. doi: 10.1016/0024-3205(79)90604-0.

DOI:10.1016/0024-3205(79)90604-0

PMID:43449

Abstract

摘要

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ICI 125,211: a new gastric antisecretory agent acting on histamine H2-receptors.ICI 125,211：一种作用于组胺H2受体的新型胃分泌抑制剂。

Life Sci. 1979 Dec 3;25(23):2001-9. doi: 10.1016/0024-3205(79)90604-0.

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Interaction of histamine with gastric mucosal cells. Effect of histamine H2 antagonists on binding and biological response.组胺与胃黏膜细胞的相互作用。组胺H2拮抗剂对结合及生物学反应的影响。

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Effects of H2-receptor antagonists cimetidine, ranitidine, and ICI 125,211 on histamine-stimulated adenylate cyclase activity in guinea pig gastric mucosa.H2受体拮抗剂西咪替丁、雷尼替丁和ICI 125,211对豚鼠胃黏膜中组胺刺激的腺苷酸环化酶活性的影响。

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Analysis of the actions of cimetidine and metiamide on gastric acid secretion in the isolated guinea pig gastric mucosa.西咪替丁和甲硫米特对豚鼠离体胃黏膜胃酸分泌作用的分析。

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In vivo and in vitro effects of CM 57755, a new gastric antisecretory agent acting on histamine H2 receptors.新型组胺H2受体作用型胃泌酸抑制剂CM 57755的体内外效应

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Conformational requirements for histamine H2-receptor inhibitors: a structure-activity study of phenylene analogues related to cimetidine and tiotidine.组胺H2受体抑制剂的构象要求：与西咪替丁和替丁相关的亚苯基类似物的构效关系研究

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Kinetics of antisecretory action of a new H2-antagonist, YM-11170, in conscious dogs.新型H2拮抗剂YM-11170对清醒犬的抗分泌作用动力学

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Inhibition of gastric acid secretion in the dog by the H2-receptor antagonists, ranitidine, cimetidine, and metiamide.H2受体拮抗剂雷尼替丁、西咪替丁和甲硫米特对犬胃酸分泌的抑制作用。

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The cardiac pharmacology of tiotidine (LCL 125, 211): a new histamine H2-receptor antagonist.替奥替丁（LCL 125, 211）的心脏药理学：一种新型组胺H2受体拮抗剂。

J Pharmacol Exp Ther. 1980 Sep;214(3):629-34.

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Agents Actions. 1982 Apr;12(1-2):138-41. doi: 10.1007/BF01965124.

Selectivity of 4-methylhistamine at H1- and H2-receptors in the guinea-pig isolated ileum.4-甲基组胺对豚鼠离体回肠H1和H2受体的选择性

Br J Pharmacol. 1983 Sep;80(1):65-71. doi: 10.1111/j.1476-5381.1983.tb11050.x.

A species comparison of the histamine H2-receptor on mast cells and basophils.肥大细胞和嗜碱性粒细胞上组胺H2受体的种属比较。

Agents Actions. 1982 Jul;12(3):263-7. doi: 10.1007/BF01965386.

A radioimmunoassay for the histamine H2-antagonist, tiotidine.一种用于组胺H2拮抗剂替丁的放射免疫测定法。

Agents Actions. 1984 Oct;15(3-4):162-6. doi: 10.1007/BF01972343.

Genetic heterogeneity of histamine H2-receptors in the mouse vas deferens.小鼠输精管中组胺H2受体的遗传异质性。

Br J Pharmacol. 1984 Nov;83(3):723-31. doi: 10.1111/j.1476-5381.1984.tb16226.x.

Cardiac effects of the new H2-receptor antagonists.新型H2受体拮抗剂的心脏效应。

Agents Actions. 1983 Apr;13(2-3):173-8. doi: 10.1007/BF01967325.

Newer antisecretory agents for peptic ulcer.用于消化性溃疡的新型抗分泌药物。

Drugs. 1983 Mar;25(3):315-30. doi: 10.2165/00003495-198325030-00003.

Clinical pharmacology of etintidine in patients with duodenal ulcer.埃替丁在十二指肠溃疡患者中的临床药理学

Eur J Clin Pharmacol. 1982;23(6):495-500. doi: 10.1007/BF00637495.

Histamine H1- and muscarinic receptor antagonist activity of cimetidine and tiotidine in the guinea pig isolated ileum.西咪替丁和替奥替丁在豚鼠离体回肠中的组胺H1和毒蕈碱受体拮抗活性。

Agents Actions. 1981 Dec;11(6-7):699-705. doi: 10.1007/BF01978792.

Inhibition by the tetramine disulphide, benextramine, of cardiac chronotropic histamine H2-receptor-mediated effects.四胺二硫化物（苄苯二胺）对心脏变时性组胺H2受体介导效应的抑制作用。

Br J Pharmacol. 1982 Apr;75(4):573-8. doi: 10.1111/j.1476-5381.1982.tb09176.x.

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