Chalon J, Patel C, Ali M, Ramanathan S, Capan L, Tang C K, Turndorf H
Anesthesiology. 1979 Mar;50(3):195-8. doi: 10.1097/00000542-197903000-00005.
Damage to the ciliated cells of the tracheobronchial tree and incidence of postoperative pulmonary complications were measured by point-scoring systems in 202 patients who breathed dry and humidified anesthetic gases for 225 +/- 78 min. The incidence of postoperative pulmonary complications decreased as the humidity of administered anesthetic gases increased from 0 to 32.5 mg H2O/l. A similar relationship was found between the amount of inhaled moisture and the damage to the ciliated epithelium of the tracheobronchial tree. These results appear to indicate that a high inspired humidity is beneficial for operations on normothermic patients, and that cellular damage caused by dryness is a possible contributory factor in the production of the pulmonary atelectasis that follows stoppage of the mucociliary transport system in the immmediate postoperative period.
通过积分系统对202例分别吸入干燥和湿化麻醉气体达225±78分钟的患者的气管支气管树纤毛细胞损伤情况及术后肺部并发症发生率进行了测定。随着所给予麻醉气体湿度从0增加至32.5mg H2O/l，术后肺部并发症的发生率降低。在吸入水分量与气管支气管树纤毛上皮损伤之间也发现了类似关系。这些结果似乎表明，高吸入湿度对体温正常患者的手术有益，并且干燥引起的细胞损伤可能是术后即刻阶段黏液纤毛运输系统停止后发生肺不张的一个促成因素。
