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骨髓增殖性疾病和淋巴增殖性疾病患者的人疱疹病毒感染

Herpesvirus hominis infection in patients with myeloproliferative and lymphoproliferative disorders.

作者信息

Aston D L, Cohen A, Spindler M A

出版信息

Br Med J. 1972 Nov 25;4(5838):462-5. doi: 10.1136/bmj.4.5838.462.

Abstract

Infection with Herpesvirus hominis, often associated with oral ulceration, was found to be more frequent in patients with myeloproliferative and lymphoproliferative disorders than in normal populations or patients with other diseases. This increased frequency was not associated with any deficiency of the humoral antibody response, suggesting a possible impairment of cell-mediated immunity. The otherwise untreatable oral lesions appeared to respond effectively to local irradiation.

摘要

人疱疹病毒感染常伴有口腔溃疡,研究发现,与正常人群或患有其他疾病的患者相比,骨髓增殖性疾病和淋巴增殖性疾病患者感染人疱疹病毒更为常见。这种感染频率的增加与体液抗体反应的任何缺陷均无关,提示可能存在细胞介导免疫功能受损。原本无法治疗的口腔病变似乎对局部照射有效。

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